Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 1965
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15559((2S)-2-[4-({[(2S)-1-[(3R)-3-amino-4-(2,4,5-trifluo...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15560((2S)-2-[4-({[(2S)-1-[(3R)-3-amino-4-(2,3,4,5,6-pen...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15561(CHEMBL427261 | (3R)-3-amino-4-(5-chloro-2-fluoroph...)
Affinity DataIC50: 21nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15562((2S)-2-[4-({[(2S)-1-[(3R)-3-amino-4-(5-fluoro-2-me...)
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15563(2-[4-({[(4R)-3-[(3R)-3-amino-4-(2-fluorophenyl)but...)
Affinity DataIC50: 37nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15564(CHEMBL363319 | (3R)-3-amino-1-(1,3-thiazolidin-3-y...)
Affinity DataIC50: 119nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15565(methyl 2-[4-({[(2S)-1-[(3R)-3-amino-4-(2-fluorophe...)
Affinity DataIC50: 170nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15566((3S)-3-{[(3S)-3-fluoropyrrolidin-1-yl]carbonyl}-7-...)
Affinity DataIC50: 310nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15567((2R,3S)-2-[4-(4-fluorophenyl)phenyl]-N,N,3-trimeth...)
Affinity DataIC50: 520nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15568((2S)-1-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]-N...)
Affinity DataIC50: 539nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15569((2S)-1-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]-N...)
Affinity DataIC50: 731nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15570((3R)-3-amino-4-[2,5-difluoro-4-(methylsulfanyl)phe...)
Affinity DataIC50: 780nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15571((2S)-1-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]-N...)
Affinity DataIC50: 864nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15572((2S)-2-amino-1-(3,3-difluoropyrrolidin-1-yl)-2-[(3...)
Affinity DataIC50: 995nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15573((3R)-3-amino-1-[4-(4-chlorophenyl)piperazin-1-yl]-...)
Affinity DataIC50: 1.25E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15574((3R)-3-amino-4-(2,5-difluorophenyl)-1-{4H,5H,6H-py...)
Affinity DataIC50: 1.33E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15575((3R)-3-amino-4-(3,4-difluorophenyl)-1-[8-(4-fluoro...)
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15576((2R,3R)-3-amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3...)
Affinity DataIC50: 1.46E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15577(2-[(1R)-1-amino-2-(2,4,5-trifluorophenyl)ethyl]-1-...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15578((3R)-3-amino-1-{4-[2-(ethenyloxy)acetyl]piperazin-...)
Affinity DataIC50: 2.21E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed