Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50019751
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 6nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50074922(2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...)
Affinity DataIC50: 10nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 10nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50074922(2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...)
Affinity DataIC50: 10nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 20nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207449(2-(1-(4-bromobenzyl)-5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207445(N-(2-(1-(4-bromobenzyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22967(2-phenylethyl 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 70nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Mouse)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 77nMAssay Description:Inhibition of mouse wild type COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207447((Z)-2-(2-(2,6-dichlorophenylamino)benzyloxyimino)p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207448(2-(2',6'-diethoxy-2-fluoro-biphenyl4-yl)-propionic...)
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207447((Z)-2-(2-(2,6-dichlorophenylamino)benzyloxyimino)p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207448(2-(2',6'-diethoxy-2-fluoro-biphenyl4-yl)-propionic...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207449(2-(1-(4-bromobenzyl)-5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22967(2-phenylethyl 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207445(N-(2-(1-(4-bromobenzyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed