Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50000675
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008524(CHEMBL152610 | Methyl-{2-[methyl-(morpholine-4-car...)
Affinity DataIC50: 1.5nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008524(CHEMBL152610 | Methyl-{2-[methyl-(morpholine-4-car...)
Affinity DataIC50: 2.40nMAssay Description:Concentration required for 50% inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 4.40nMAssay Description:Concentration required for 50% inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 4.5nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 11nMAssay Description:Concentration required for 50% inhibition of rhesus monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008522(CHEMBL427931 | 4-Amino-cyclohexanecarboxylic acid ...)
Affinity DataIC50: 12nMAssay Description:Concentration required for 50% inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008522(CHEMBL427931 | 4-Amino-cyclohexanecarboxylic acid ...)
Affinity DataIC50: 22nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50230367(CHEMBL3143442)
Affinity DataIC50: 50nMAssay Description:Concentration required for 50% inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 100nMAssay Description:Concentration required for 50% inhibition of sheep plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50230367(CHEMBL3143442)
Affinity DataIC50: 110nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 110nMAssay Description:Concentration required for 50% inhibition of dog plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50230366(CHEMBL3143445)
Affinity DataIC50: 120nMAssay Description:Concentration required for 50% inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50230366(CHEMBL3143445)
Affinity DataIC50: 420nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Rat)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required for 50% inhibition of rat plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPepsin A-5(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 1.00E+6nMAssay Description:Concentration required for 50% inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed