Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50020004
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209580([Ncy(isopropyl)7]acyline | CHEMBL415659)
Affinity DataIC50: 0.310nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50102456(acyline | Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)...)
Affinity DataIC50: 0.520nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209587([D-Ncy(methyl)10] acyline | CHEMBL387499)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209594([D-Ncy(2-naphthyl)1]acyline | CHEMBL227861)
Affinity DataIC50: 0.730nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209583([Ncy(methyl)10]acyline | CHEMBL427438)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209590([D-Ncy(isopropyl)7]acyline | CHEMBL227451)
Affinity DataIC50: 0.810nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209599([D-Ncy(SO,methyl)10]acyline | CHEMBL434371)
Affinity DataIC50: 0.830nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209598([Ncy(SO,methyl)10]acyline | CHEMBL389248)
Affinity DataIC50: 0.870nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209595([Ncy(SO,isopropyl)7]acyline | CHEMBL441211)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209582([Ncy(methyl)4]acyline | CHEMBL388369)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209591(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Atz)]-D-[Aph(...)
Affinity DataIC50: 1.36nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209591(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Atz)]-D-[Aph(...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50102456(acyline | Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209587([D-Ncy(methyl)10] acyline | CHEMBL387499)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209583([Ncy(methyl)10]acyline | CHEMBL427438)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209585([Ncy(2-naphthyl)1]acyline | CHEMBL414344)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209582([Ncy(methyl)4]acyline | CHEMBL388369)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209580([Ncy(isopropyl)7]acyline | CHEMBL415659)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209588([D-Ncy(SO,isopropyl)7]acyline | CHEMBL427269)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209595([Ncy(SO,isopropyl)7]acyline | CHEMBL441211)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209594([D-Ncy(2-naphthyl)1]acyline | CHEMBL227861)
Affinity DataIC50: 4.40nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209586([Ncy(SO,methyl)4]acyline | CHEMBL415432)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209593([D-Gln3,Ncy(isopropyl)7]acyline | CHEMBL228197)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209581([D-Ncy(SO,methyl)4]acyline | CHEMBL389945)
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209596([D-Gln3,Ncy(SO,isopropyl)7]acyline | CHEMBL425486)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209597([D-Ncy(methyl)4]acyline | CHEMBL268297)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209589([D-Gln3,D-Ncy(isopropyl)7]acyline | CHEMBL428795)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209584([D-Gln3,D-Ncy(SO,isopropyl)7]acyline | CHEMBL41538...)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209592([D-Gln3,D-Ncy(SO2,isopropyl)7]acyline | CHEMBL3737...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209600([D-Gln3,Ncy(SO2,isopropyl)7]acyline | CHEMBL373724)
Affinity DataIC50: 3.82E+3nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed