Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50020026
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1...)
Affinity DataEC50:  116nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-2,3-...)
Affinity DataEC50:  301nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-3,4-dihydro-2...)
Affinity DataEC50:  332nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-3,4-dihydro-2...)
Affinity DataEC50:  332nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-2,3-...)
Affinity DataEC50:  301nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1...)
Affinity DataEC50:  116nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-3,4-dihydro-2...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-3,4-dihydro-2...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209682(N-(4-(5-fluoro-1H-indol-3-yl)butyl)-3,4-dihydro-2H...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-3,4-dihydro-2...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-2,3-...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191639(N-[3-(5-Fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-p...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209681(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-5-methoxy-3,4...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209675(N-(4-(5-fluoro-1H-indol-3-yl)butyl)-N-propyl-3,4-d...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209680(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-3,4-...)
Affinity DataKi:  12.4nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191639(N-[3-(5-Fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-p...)
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-2,3-...)
Affinity DataKi:  19.8nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-2,3-...)
Affinity DataKi:  19.8nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1...)
Affinity DataKi:  23.9nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209678(N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2,3-dihydro-1H...)
Affinity DataKi:  30.5nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-2,3-...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-2,3-...)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209676(N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-N-propyl-2,3-d...)
Affinity DataKi:  62.8nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake site of rat cortical 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209677(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-propyl-2,3-...)
Affinity DataKi:  63.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-3,4-dihydro-2...)
Affinity DataKi:  67.8nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-3,4-dihydro-2...)
Affinity DataKi:  67.8nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209681(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-5-methoxy-3,4...)
Affinity DataKi:  70.4nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1...)
Affinity DataKi:  313nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209679(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-2,3-dihydro-1...)
Affinity DataKi:  314nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209674(N-(3-(5-fluoro-1H-indol-3-yl)propyl)-3,4-dihydro-2...)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209676(N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-N-propyl-2,3-d...)
Affinity DataKi:  478nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed