Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 2032
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16240(2-(carboxymethyl)-1-oxo-1,2-dihydronaphtho[1,2-d]i...)
Affinity DataIC50: 140nMpH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16242(2-{[4-(carboxymethyl)-3,5,5-trioxo-5-thia-4-azatri...)
Affinity DataIC50: 550nMpH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16243(2-(3,5,5-trioxo-5-thia-4-azatricyclo[7.4.0.0^{2,6}...)
Affinity DataIC50: 1.00E+4nMpH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16248(4-methyl-3,5,5-trioxo-5-thia-4-azatricyclo[7.4.0.0...)
Affinity DataIC50: 8.80E+4nMpH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16246(2-(13-amino-3,5,5-trioxo-5-thia-4-azatricyclo[7.4....)
Affinity DataIC50: 1.00E+5nMpH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16247(2-(10-amino-3,5,5-trioxo-5-thia-4-azatricyclo[7.4....)
Affinity DataIC50: 1.00E+5nMpH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16245(2-(10-nitro-3,5,5-trioxo-5-thia-4-azatricyclo[7.4....)
Affinity DataIC50: 1.80E+5nMpH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16244(2-(13-nitro-3,5,5-trioxo-5-thia-4-azatricyclo[7.4....)
Affinity DataIC50: 1.90E+5nMpH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Marburg

LigandPNGBDBM16249(2-[(4-methyl-3,5,5-trioxo-5-thia-4-azatricyclo[7.4...)
Affinity DatapH: 6.2 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the oxidation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed