Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50025170
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269975(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  0.0600nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269976(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataEC50:  0.150nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269978(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Fl...)
Affinity DataEC50:  0.920nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269976(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataEC50:  1.10nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269977(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataEC50:  1.10nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269976(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataEC50:  2.20nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269976(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataIC50: 6.87nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269978(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Fl...)
Affinity DataEC50:  7.20nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269975(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataIC50: 7.20nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269974(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  13nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269978(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Fl...)
Affinity DataIC50: 13.5nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269977(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataEC50:  20nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269976(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataKd:  21.6nMAssay Description:Binding affinity to PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269973(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  26nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269976(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataEC50:  26nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269971(Ala-Val-Ala-Glu-lle-Gln-Leu-Met-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  32nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269972(Ala-Val-Ala-Glu-lle-Gln-Leu-Met-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  53nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269976(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataIC50: 55.4nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cells in presence of SW106More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269977(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Ly...)
Affinity DataIC50: 98.2nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269973(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  129nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269971(Ala-Val-Ala-Glu-lle-Gln-Leu-Met-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  155nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269972(Ala-Val-Ala-Glu-lle-Gln-Leu-Met-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  251nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269974(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  344nMAssay Description:Activity at rat PTH/PTH-related peptide receptor expressed in rat UMR106 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269971(Ala-Val-Ala-Glu-lle-Gln-Leu-Met-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  800nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269979(r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-...)
Affinity DataIC50: 990nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269972(Ala-Val-Ala-Glu-lle-Gln-Leu-Met-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  1.00E+3nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269974(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  1.43E+3nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269973(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataEC50:  1.46E+3nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269973(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataIC50: 2.19E+3nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269979(r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-...)
Affinity DataIC50: 5.78E+3nMAssay Description:Antagonist activity at PTH/PTH-related peptide receptor expressed in HKRK-B28 cells assessed as inhibition of DPC-AJ1951-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269972(Ala-Val-Ala-Glu-lle-Gln-Leu-Met-His-Gln-Har-Ala-Ly...)
Affinity DataIC50: 1.01E+4nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269979(r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-...)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of adrenergic Alpha-2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269971(Ala-Val-Ala-Glu-lle-Gln-Leu-Met-His-Gln-Har-Ala-Ly...)
Affinity DataIC50: 1.05E+4nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269974(Ala-Val-Ala-Glu-lle-Gln-Leu-Nle-His-Gln-Har-Ala-Ly...)
Affinity DataIC50: 1.06E+4nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269979(r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-...)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269979(r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269979(r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of neurokinin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269979(r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-...)
Affinity DataIC50: 6.80E+4nMAssay Description:Antagonist activity at PTH/PTH-related peptide receptor expressed in HKRK-B28 cells assessed as inhibition of parathyroid hormone (1 to 34)-induced c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed