Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50038377
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 20nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375600(CHEMBL407109)
Affinity DataIC50: 28nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375600(CHEMBL407109)
Affinity DataIC50: 33nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 35nMAssay Description:Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 35nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375607(CHEMBL259218)
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375607(CHEMBL259218)
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375601(CHEMBL76154)
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375601(CHEMBL76154)
Affinity DataIC50: 48nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 58nMAssay Description:Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375603(CHEMBL407368)
Affinity DataIC50: 60nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375607(CHEMBL259218)
Affinity DataIC50: 63nMAssay Description:Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375607(CHEMBL259218)
Affinity DataIC50: 63nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 67nMAssay Description:Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375600(CHEMBL407109)
Affinity DataIC50: 77nMAssay Description:Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375603(CHEMBL407368)
Affinity DataIC50: 94nMAssay Description:Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375603(CHEMBL407368)
Affinity DataIC50: 94nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: 107nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human COX2 mediated PGE2 production in IL-1-beta-induced human dermal fibroblast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human COX2 mediated PGE2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375605(CHEMBL258738)
Affinity DataIC50: 166nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375604(CHEMBL259842)
Affinity DataIC50: 174nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375604(CHEMBL259842)
Affinity DataIC50: 174nMAssay Description:Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375601(CHEMBL76154)
Affinity DataIC50: 234nMAssay Description:Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375605(CHEMBL258738)
Affinity DataIC50: 241nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375604(CHEMBL259842)
Affinity DataIC50: 327nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375602(CHEMBL408156)
Affinity DataIC50: 629nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375605(CHEMBL258738)
Affinity DataIC50: 696nMAssay Description:Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375602(CHEMBL408156)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375604(CHEMBL259842)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataKi:  320nMAssay Description:Inhibition of human COX2 preincubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375607(CHEMBL259218)
Affinity DataKi:  820nMAssay Description:Inhibition of mouse COX2 pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375607(CHEMBL259218)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human COX2 preincubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375607(CHEMBL259218)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of ovine COX1 pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataKi:  7.90E+3nMAssay Description:Inhibition of ovine COX1 pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed