Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 2188
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataKi:  14nM ΔG°:  -45.6kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM12287(tert-butyl N-[(1S)-2-[(1R,2S,5S)-2-[(1-carbamoyl-3...)
Affinity DataKi:  15nM ΔG°:  -45.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17886(3-{[(1S,5R)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  19nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17898(N-{1-[(1R,5S)-2-[(1-carbamoyl-3-cyclobutyl-1-oxopr...)
Affinity DataKi:  38nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17884(3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  50nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17875(3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-2-cy...)
Affinity DataKi:  54nM ΔG°:  -42.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM12297(1,1-Dimethylethyl-[1(S)-[[(1R,5S)-2(S)-[[[3-amino-...)
Affinity DataKi:  57nM ΔG°:  -42.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17896(propan-2-yl N-{2-[(1R,5S)-2-[(1-carbamoyl-3-cyclop...)
Affinity DataKi:  60nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17897(N-{2-[(1R,5S)-2-[(1-carbamoyl-3-cyclopropyl-1-oxop...)
Affinity DataKi:  68nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17882(3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  100nM ΔG°:  -40.6kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17893(3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-3-me...)
Affinity DataKi:  100nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17885(3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  115nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17887(3-{[(1S,5R)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  140nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17876(tert-butyl N-{1-[(1R,5S)-2-[(1-carbamoyl-1-oxopent...)
Affinity DataKi:  220nM ΔG°:  -38.6kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17895(ethyl N-{2-[(1R,5S)-2-[(1-carbamoyl-3-cyclopropyl-...)
Affinity DataKi:  230nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17877(tert-butyl N-{1-[(1R,5S)-2-[(1-carbamoyl-1-oxohexa...)
Affinity DataKi:  360nM ΔG°:  -37.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17878(tert-butyl N-{1-[(1R,5S)-2-[(1-carbamoyl-4-methyl-...)
Affinity DataKi:  480nM ΔG°:  -36.7kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17888(3-{[(3aR,6aR)-5-{2-[(tert-butylcarbamoyl)amino]-3,...)
Affinity DataKi:  500nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17894(methyl N-{2-[(1R,5S)-2-[(1-carbamoyl-3-cyclopropyl...)
Affinity DataKi:  800nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17890(3-{[(1R,5R)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  960nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17891(2-{2-[(tert-butylcarbamoyl)amino]-3,3-dimethylbuta...)
Affinity DataKi:  1.00E+3nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17874(tert-butyl N-[(1S)-2-[(1R,2S,5R)-2-[(1-carbamoyl-3...)
Affinity DataKi:  1.40E+3nM ΔG°:  -34.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17881(3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  1.60E+3nM ΔG°:  -33.6kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17883(3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  1.80E+3nM ΔG°:  -33.3kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17879(tert-butyl N-{1-[(1R,5S)-2-[(1-carbamoyl-4,4-dimet...)
Affinity DataKi: >3.30E+3nM ΔG°: >-31.8kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17873((2S)-2-(2-{3-[(2S)-4-methyl-2-[(4E)-7-methyl-2-(pr...)
Affinity DataKi:  4.30E+3nM ΔG°:  -31.1kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17889(3-[(1-{2-[(tert-butylcarbamoyl)amino]-3,3-dimethyl...)
Affinity DataKi:  5.00E+3nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17892(tert-butyl N-[1-({1-[(1-carbamoyl-3-cyclobutyl-1-o...)
Affinity DataKi:  1.50E+4nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17880(tert-butyl N-{1-[(1R,5S)-2-[(1-carbamoyl-3,3-dimet...)
Affinity DataKi: >6.90E+4nM ΔG°: >-24.1kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed