Compile Data Set for Download or QSAR
Report error Found 107 Enz. Inhib. hit(s) with all data for entry = 2017
LigandPNGBDBM16171(2-[4-chloro-7-({1-[(4-methylpiperazin-1-yl)carbony...)
Affinity DataKi:  1.40nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16170(2-(4-chloro-7-{[1-(morpholin-4-ylcarbonyl)cyclopen...)
Affinity DataKi:  1.60nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16165(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  2.60nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16154(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  5.80nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16153(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  7.40nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16156(4-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  7.40nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16155(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  8nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16159((2R)-1-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  9.90nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16152(substituted glycine deriv. 26 | 2-({4-chloro-1-[(d...)
Affinity DataKi:  10nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16169(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  10nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16164(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  11nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16157(4-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  11nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16166(ethyl 1-({4-chloro-1-[(diaminomethylidene)amino]is...)
Affinity DataKi:  14nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16129(1-isoquinolinylguanidine 3 | 3-{4-chloro-1-[(diami...)
Affinity DataKi:  17nM ΔG°:  -46.1kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16148((2R)-2-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  19nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16147((2S)-2-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  21nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16150((2R)-2-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  22nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16161((2R)-1-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  23nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16151((2S)-2-[benzyl({4-chloro-1-[(diaminomethylidene)am...)
Affinity DataKi:  27nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16146((2R)-2-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  28nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16143(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  29nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16168(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  30nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16145(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  31nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16144(2-[benzyl({4-chloro-1-[(diaminomethylidene)amino]i...)
Affinity DataKi:  35nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16141(3-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  43nM ΔG°:  -43.7kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16139(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  48nM ΔG°:  -43.5kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16163((2R)-1-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  54nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16142(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  54nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16140(3-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  58nM ΔG°:  -43.0kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16138(3-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  59nM ΔG°:  -42.9kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16149((2S)-2-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  66nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16167(2-(4-chloro-7-{[1-(hydroxymethyl)cyclopentyl]sulfa...)
Affinity DataKi:  67nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16133(2-[4-chloro-7-(cyclopentylsulfamoyl)isoquinolin-1-...)
Affinity DataKi:  71nM ΔG°:  -42.4kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16137(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  86nM ΔG°:  -42.0kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16160((2S)-1-({4-chloro-1-[(diaminomethylidene)amino]iso...)
Affinity DataKi:  111nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16134(2-[4-chloro-7-(pyrrolidine-1-sulfonyl)isoquinolin-...)
Affinity DataKi:  130nM ΔG°:  -40.9kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16132(2-(4-chloro-7-sulfamoylisoquinolin-1-yl)guanidine ...)
Affinity DataKi:  140nM ΔG°:  -40.7kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16162(2-(4-chloro-7-{[(2R)-2-(hydroxymethyl)pyrrolidine-...)
Affinity DataKi:  160nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16131(2-[7-(phenylsulfamoyl)isoquinolin-1-yl]guanidine |...)
Affinity DataKi:  160nM ΔG°:  -40.3kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16130(2-(7-sulfamoylisoquinolin-1-yl)guanidine | 1-guani...)
Affinity DataKi:  280nM ΔG°:  -38.9kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16135(2-[4-chloro-7-(morpholine-4-sulfonyl)isoquinolin-1...)
Affinity DataKi:  330nM ΔG°:  -38.5kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16158(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  330nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16136(2-{4-chloro-7-[(4-methylpiperazine-1-)sulfonyl]iso...)
Affinity DataKi:  550nM ΔG°:  -37.2kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16127(CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...)
Affinity DataKi:  2.30E+3nM ΔG°:  -33.5kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetPlasminogen(Human)
Pfizer

LigandPNGBDBM16131(2-[7-(phenylsulfamoyl)isoquinolin-1-yl]guanidine |...)
Affinity DataKi:  3.20E+3nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16128(4-(trifluoromethyl)benzene-1-guanidine | CHEMBL439...)
Affinity DataKi:  6.00E+3nM ΔG°:  -31.0kJ/molepH: 8.1 T: 2°CAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetPlasminogen(Human)
Pfizer

LigandPNGBDBM16138(3-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  9.80E+3nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetPlasminogen(Human)
Pfizer

LigandPNGBDBM16130(2-(7-sulfamoylisoquinolin-1-yl)guanidine | 1-guani...)
Affinity DataKi:  1.30E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetPlasminogen(Human)
Pfizer

LigandPNGBDBM16154(1-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  1.40E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16131(2-[7-(phenylsulfamoyl)isoquinolin-1-yl]guanidine |...)
Affinity DataKi:  1.50E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
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