Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 2472
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21022(H-Tyr-D-Ala-Gly-Phe-Met(O)-Pro-Leu-Trp-O-3,5-Bzl(C...)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21021(H-Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-O-3,5-Bzl(CF3)...)
Affinity DataKi:  0.290nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21023([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21024(H-Tyr-D-Ala-Gly-Phe-N-Me-Nle-Pro-Leu-Trp-O-3,5-Bzl...)
Affinity DataKi:  0.710nM ΔG°:  -52.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21020(H-Tyr-D-Ala-Gly-Phe-Leu-Pro-Leu-Trp-O-3,5-Bzl(CF3)...)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21017([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  0.880nM ΔG°:  -51.7kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21019([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/mole EC50:  1.10nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21025([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...)
Affinity DataKi:  1.30nM ΔG°:  -50.7kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21022(H-Tyr-D-Ala-Gly-Phe-Met(O)-Pro-Leu-Trp-O-3,5-Bzl(C...)
Affinity DataKi:  4.80nM ΔG°:  -47.5kJ/mole EC50:  1.80nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21023([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  1.80nM ΔG°:  -49.9kJ/mole EC50:  4nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21021(H-Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-O-3,5-Bzl(CF3)...)
Affinity DataKi:  2.80nM ΔG°:  -48.8kJ/mole EC50:  2.90nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21018(H-Tyr-D-Ala-Gly-Phe-D-Phe-Pro-Leu-Trp-O-3,5-Bzl(CF...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21020(H-Tyr-D-Ala-Gly-Phe-Leu-Pro-Leu-Trp-O-3,5-Bzl(CF3)...)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/mole EC50:  9.60nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21022(H-Tyr-D-Ala-Gly-Phe-Met(O)-Pro-Leu-Trp-O-3,5-Bzl(C...)
Affinity DataKi:  5.5nM ΔG°:  -47.1kJ/mole EC50:  34nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21023([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  9.70nM ΔG°:  -45.7kJ/mole EC50:  28nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21017([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  15nM ΔG°:  -44.7kJ/mole EC50:  21nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21025([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...)
Affinity DataKi:  15nM ΔG°:  -44.7kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21018(H-Tyr-D-Ala-Gly-Phe-D-Phe-Pro-Leu-Trp-O-3,5-Bzl(CF...)
Affinity DataKi:  93nM ΔG°:  -40.1kJ/mole EC50:  17nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21020(H-Tyr-D-Ala-Gly-Phe-Leu-Pro-Leu-Trp-O-3,5-Bzl(CF3)...)
Affinity DataKi:  23nM ΔG°:  -43.6kJ/mole EC50:  33nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21019([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/mole EC50:  42nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21017([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  28nM ΔG°:  -43.1kJ/mole EC50:  59nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21021(H-Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-O-3,5-Bzl(CF3)...)
Affinity DataKi:  36nM ΔG°:  -42.5kJ/mole EC50:  32nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21019([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S...)
Affinity DataKi:  36nM ΔG°:  -42.5kJ/mole EC50:  50nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona Tucson

LigandPNGBDBM21024(H-Tyr-D-Ala-Gly-Phe-N-Me-Nle-Pro-Leu-Trp-O-3,5-Bzl...)
Affinity DataKi:  77nM ΔG°:  -40.6kJ/mole EC50:  360nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21016([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acet...)
Affinity DataKi:  134nM ΔG°:  -39.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21024(H-Tyr-D-Ala-Gly-Phe-N-Me-Nle-Pro-Leu-Trp-O-3,5-Bzl...)
Affinity DataKi:  140nM ΔG°:  -39.1kJ/mole EC50:  150nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona Tucson

LigandPNGBDBM21018(H-Tyr-D-Ala-Gly-Phe-D-Phe-Pro-Leu-Trp-O-3,5-Bzl(CF...)
Affinity DataKi:  380nM ΔG°:  -36.6kJ/mole EC50:  350nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed