Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50020500
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50024779(CHEMBL248194)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214574((S)-3-[3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-2,4-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214561((R)-3-[3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-2,4-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214594(4'-{6-methoxy-7-[3-(4-methyl-piperazin-1-yl)-propo...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214602(4'-[7-methoxy-6-(tetrahydro-pyran-4-yloxy)-2,4-dih...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214580(4'-[7-methoxy-6-(tetrahydro-furan-3-yloxy)-2,4-dih...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214585(4'-[7-(1-ethyl-piperidin-3-yloxy)-6-methoxy-2,4-di...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214586(4'-[7-(3-dimethylamino-2-methyl-propoxy)-6-methoxy...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214595(4'-[6-((R)-1-cyclohex-3-enylmethoxy)-7-methoxy-2,4...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214576(4'-[6-(3-dimethylamino-propoxy)-7-methoxy-2,4-dihy...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214560(4'-[7-methoxy-6-(2-pyrrolidin-1-yl-ethoxy)-2,4-dih...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214590(4'-[7-(2-dimethylamino-ethoxy)-6-methoxy-2,4-dihyd...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214603(4'-{6-methoxy-7-[2-(1-methyl-pyrrolidin-2-yl)-etho...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214565(4'-[7-methoxy-6-(tetrahydro-furan-3-ylmethoxy)-2,4...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214599(3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-2,4-dihydro...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214582(4'-[7-methoxy-6-(2-piperidin-1-yl-ethoxy)-2,4-dihy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214577(Chk1_115 | CHEMBL245796 | 4'-(6,7-dimethoxy-1,4-di...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214600(4'-[7-methoxy-6-(2-morpholin-4-yl-ethoxy)-2,4-dihy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214575(4'-[7-(2-dimethylamino-1-methyl-ethoxy)-6-methoxy-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214557(4'-[6-(2-dimethylamino-ethoxy)-7-methoxy-2,4-dihyd...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214598(4'-[6-methoxy-7-(2-pyrrolidin-1-yl-ethoxy)-2,4-dih...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214570(4'-[6-(2-dimethylamino-1-methyl-ethoxy)-7-methoxy-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214605(4'-[7-methoxy-6-((S)-2-pyrrolidin-2-yl-ethoxy)-2,4...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214589(4'-[7-(2-diethylamino-1-diethylaminomethyl-ethoxy)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214568(4'-[7-(2-imidazol-1-yl-ethoxy)-6-methoxy-2,4-dihyd...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214566(4'-[7-methoxy-6-(3-piperidin-1-yl-propoxy)-2,4-dih...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214563(4'-[6-methoxy-7-(2-morpholin-4-yl-ethoxy)-2,4-dihy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214578(4'-[7-methoxy-6-(2-pyridin-4-yl-ethoxy)-2,4-dihydr...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214559(CHEMBL248200 | Chk1_130 | 3-(4'-hydroxy-biphenyl-4...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214569(4'-[6-(2-iImidazol-1-yl-ethoxy)-7-methoxy-2,4-dihy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214597(4'-[7-methoxy-6-(3-morpholin-4-yl-propoxy)-2,4-dih...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214592(4'-(6-{3-[4-(3-chloro-phenyl)-piperazin-1-yl]-prop...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214588(4'-[7-methoxy-6-(pyridin-4-ylmethoxy)-2,4-dihydro-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214591(4'-(7-{3-[4-(3-chloro-phenyl)-piperazin-1-yl]-prop...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214601(4'-[7-methoxy-6-(2-pyridin-3-yl-ethoxy)-2,4-dihydr...)
Affinity DataIC50: 13nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214579(4'-[7-methoxy-6-(pyridin-3-ylmethoxy)-2,4-dihydro-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214587(4'-[7-methoxy-6-(pyridin-2-ylmethoxy)-2,4-dihydro-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214573((2-pyrrolidin-1-yl-ethyl)-carbamic acid 3-(4'-hydr...)
Affinity DataIC50: 21nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214581(4'-[6-methoxy-7-(pyridin-3-ylmethoxy)-2,4-dihydro-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214567(Chk1_135 | CHEMBL248010 | 4'-{6-[2-(5-ethyl-pyridi...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214584(4'-[6-methoxy-7-(pyridin-2-ylmethoxy)-2,4-dihydro-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214596(4'-(7-methoxy-6-{3-[4-(2-methoxy-phenyl)-piperazin...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214564(4'-[7-methoxy-6-(2-pyridin-2-yl-ethoxy)-2,4-dihydr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214583(4'-[6-methoxy-7-(pyridin-4-ylmethoxy)-2,4-dihydro-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214593((2-dimethylamino-ethyl)-carbamic acid 3-(4'-hydrox...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214604(pyridin-2-ylmethyl-carbamic acid 3-(4'-hydroxy-bip...)
Affinity DataIC50: 48nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214572(4'-(7-methoxy-6-{2-[3-(6-methyl-pyridin-2-yl)-prop...)
Affinity DataIC50: 62nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214558((2-morpholin-4-yl-ethyl)-carbamic acid 3-(4'-hydro...)
Affinity DataIC50: 74nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214571(4'-(6-methoxy-7-trifluoromethoxy-2,4-dihydro-inden...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed