Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50020549
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215008(4-(1,3-dioxo-1,3-bis(phenylamino)propan-2-yl)-N-hy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215018(4-(1,3-bis(2,3-dihydrobenzo[b][1,4]dioxin-6-ylamin...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215015(4-(1,3-bis(3-cyanophenylamino)-1,3-dioxopropan-2-y...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215016(4-(1,3-bis(3-methoxyphenylamino)-1,3-dioxopropan-2...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215014(4-(1,3-bis(3-morpholinophenylamino)-1,3-dioxopropa...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215013(N-(2-aminophenyl)-4-(3-oxo-3-(phenylamino)-2-(phen...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215003(4-(1,3-bis(2-methoxyphenylamino)-1,3-dioxopropan-2...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215012(N-(2-aminophenyl)-4-(2-fluoro-1,3-dioxo-1,3-bis(ph...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215004(4-(1,3-bis(3-fluorophenylamino)-1,3-dioxopropan-2-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215005(4-(1,3-bis(4-fluorophenylamino)-1,3-dioxopropan-2-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215009(N-(2-aminophenyl)-4-(2-hydroxy-1,3-dioxo-1,3-bis(p...)
Affinity DataIC50: 94nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215011(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(quinolin-8-...)
Affinity DataIC50: 103nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215017(N-(2-aminophenyl)-4-(3-(methyl(phenyl)amino)-1,3-d...)
Affinity DataIC50: 196nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215021(N-(2-aminophenyl)-4-(2-methyl-1,3-dioxo-1,3-bis(ph...)
Affinity DataIC50: 198nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215002(4-(1,3-bis(benzylamino)-1,3-dioxopropan-2-yl)-N-(2...)
Affinity DataIC50: 199nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215007(N-(2-aminophenyl)-4-(2-methyl-3-oxo-3-(phenylamino...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215006(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(3-phenylpro...)
Affinity DataIC50: 229nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 313nMAssay Description:Inhibition of human HDAC2 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 697nMAssay Description:Inhibition of human HDAC3 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215019(4-tert-butyl-N-hydroxybenzamide | CHEMBL249284)
Affinity DataIC50: 715nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215020(4-(1,3-bis(methyl(phenyl)amino)-1,3-dioxopropan-2-...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015184(benzoyl hydroxamic acid | CHEMBL16300 | BENZHYDROX...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099857(acetohydroxamic acid | AHA | Acethydroxamsaeure | ...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed