Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 2928
LigandPNGBDBM26166(3-({4-[(5-hydroxy-2-methylphenyl)amino]pyrimidin-2...)
Affinity DataIC50: 8.5nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26180(3-({4-[(5-methyl-1H-indazol-4-yl)amino]pyrimidin-2...)
Affinity DataIC50: 12nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26145(CHEMBL249097 | 3-({4-[(5-hydroxy-2-methylphenyl)am...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26186(3-({4-[(5-methyl-1H-indazol-4-yl)amino]pyrimidin-2...)
Affinity DataIC50: 19nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26185(3-{[4-(1H-indazol-4-ylamino)pyrimidin-2-yl]amino}b...)
Affinity DataIC50: 33nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26152(3-({4-[(4-hydroxy-2-methylphenyl)amino]pyrimidin-2...)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26149(3-({4-[(2-bromo-5-hydroxyphenyl)amino]pyrimidin-2-...)
Affinity DataIC50: 41nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26167(3-({4-[(5-methoxy-2-methylphenyl)amino]pyrimidin-2...)
Affinity DataIC50: 54nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26182(3-({4-[(7-methyl-1H-indazol-4-yl)amino]pyrimidin-2...)
Affinity DataIC50: 55nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM25191(BMCL18318 Compound 1 | 4-{4-[(5-hydroxy-2-methylph...)
Affinity DataIC50: 59nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26147(3-({4-[(3-hydroxy-5-methylphenyl)amino]pyrimidin-2...)
Affinity DataIC50: 73nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26156(3-({4-[(5-methoxy-2-methylphenyl)amino]pyrimidin-2...)
Affinity DataIC50: 86nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26151(3-({4-[(2-methylphenyl)amino]pyrimidin-2-yl}amino)...)
Affinity DataIC50: 89nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26157(3-({4-[(5-amino-2-methylphenyl)amino]pyrimidin-2-y...)
Affinity DataIC50: 97nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26179(3-{[4-(1H-indazol-4-ylamino)pyrimidin-2-yl]amino}b...)
Affinity DataIC50: 100nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26153(3-({4-[(2-hydroxy-6-methylphenyl)amino]pyrimidin-2...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26146(3-({4-[(3-hydroxyphenyl)amino]pyrimidin-2-yl}amino...)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26148(3-({4-[(3-hydroxy-4-methylphenyl)amino]pyrimidin-2...)
Affinity DataIC50: 190nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26154(3-({4-[(5-fluoro-2-methylphenyl)amino]pyrimidin-2-...)
Affinity DataIC50: 270nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26168(3-({4-[(2,4-difluorophenyl)amino]pyrimidin-2-yl}am...)
Affinity DataIC50: 350nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26155(3-({4-[(5-chloro-2-methylphenyl)amino]pyrimidin-2-...)
Affinity DataIC50: 380nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26176(3-{[4-(1H-1,2,3-benzotriazol-7-ylamino)pyrimidin-2...)
Affinity DataIC50: 490nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26181(3-({4-[(6-methyl-1H-indazol-4-yl)amino]pyrimidin-2...)
Affinity DataIC50: 520nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26175(3-{[4-(quinolin-5-ylamino)pyrimidin-2-yl]amino}ben...)
Affinity DataIC50: 560nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26150(3-[(4-{[5-hydroxy-2-(propan-2-yl)phenyl]amino}pyri...)
Affinity DataIC50: 880nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26165(3-({4-[(2,4-difluorophenyl)amino]pyrimidin-2-yl}am...)
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26158(3-({2-[(3-carbamoylphenyl)amino]pyrimidin-4-yl}ami...)
Affinity DataIC50: 1.30E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26177(3-{[4-(1H-indazol-7-ylamino)pyrimidin-2-yl]amino}b...)
Affinity DataIC50: 1.40E+3nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26183(3-({4-[(1-methyl-1H-indazol-4-yl)amino]pyrimidin-2...)
Affinity DataIC50: 1.60E+3nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26164(3-[(4-{[3-(N-methylacetamido)phenyl]amino}pyrimidi...)
Affinity DataIC50: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26172(3-({4-[(1-methyl-1H-1,3-benzodiazol-5-yl)amino]pyr...)
Affinity DataIC50: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26162(3-({4-[(3-methoxyphenyl)amino]pyrimidin-2-yl}amino...)
Affinity DataIC50: 2.70E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26184(3-({4-[(1,5-dimethyl-1H-indazol-4-yl)amino]pyrimid...)
Affinity DataIC50: 2.80E+3nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26169(3-{[4-(1,3-benzothiazol-6-ylamino)pyrimidin-2-yl]a...)
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26171(3-{[4-(1H-indazol-5-ylamino)pyrimidin-2-yl]amino}b...)
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26163(3-({4-[(3-fluorophenyl)amino]pyrimidin-2-yl}amino)...)
Affinity DataIC50: 3.30E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26161(3-[(4-{[5-(aminomethyl)-2-methylphenyl]amino}pyrim...)
Affinity DataIC50: 3.40E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26173(3-{[4-(1H-1,2,3-benzotriazol-6-ylamino)pyrimidin-2...)
Affinity DataIC50: 4.40E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26178(3-({4-[(2-methyl-1H-1,3-benzodiazol-4-yl)amino]pyr...)
Affinity DataIC50: 5.60E+3nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26160(3-({4-[(5-methanesulfonamido-2-methylphenyl)amino]...)
Affinity DataIC50: 7.70E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26174(3-({4-[(1-methyl-1H-indazol-6-yl)amino]pyrimidin-2...)
Affinity DataIC50: 8.20E+3nMAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26159(3-({2-[(3-carbamoylphenyl)amino]pyrimidin-4-yl}ami...)
Affinity DataIC50: 9.30E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
LigandPNGBDBM26170(3-({4-[(1-methyl-1H-1,3-benzodiazol-6-yl)amino]pyr...)
Affinity DataIC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed