Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 2423
LigandPNGBDBM20317(3-[(4-tert-butylphenyl)methyl]-1-[(1R)-1-(4-methan...)
Affinity DataKi:  41nM ΔG°:  -43.9kJ/mole EC50:  4.5nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20321(JYL1421 | CHEMBL388824 | 3-[(4-tert-butylphenyl)me...)
Affinity DataKi:  53.5nM ΔG°:  -43.2kJ/mole EC50:  9.20nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20322(3-[(4-tert-butylphenyl)methyl]-1-[1-(3-fluoro-4-me...)
Affinity DataKi:  54nM ΔG°:  -43.2kJ/mole EC50:  9.20nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20316(3-[(4-tert-butylphenyl)methyl]-1-[1-(4-methanesulf...)
Affinity DataKi:  59.3nM ΔG°:  -42.9kJ/mole EC50:  14.7nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20331(3-[(4-tert-butylphenyl)methyl]-1-[1-(4-methanesulf...)
Affinity DataKi:  67nM ΔG°:  -42.6kJ/mole EC50:  28.6nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20323(3-[(4-tert-butylphenyl)methyl]-1-[(1R)-1-(3-fluoro...)
Affinity DataKi:  39.2nM ΔG°:  -44.0kJ/mole EC50:  37nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20330(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataKi:  51nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20325(3-[(4-tert-butylphenyl)methyl]-1-[1-(3-fluoro-4-me...)
Affinity DataKi:  230nM ΔG°:  -39.4kJ/mole EC50:  54nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20315(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataKi:  63nM ΔG°:  -42.8kJ/mole EC50:  54nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20320(1-[(4-tert-butylphenyl)methyl]-3-[1-(4-methanesulf...)
Affinity DataKi:  171nM ΔG°:  -40.2kJ/mole EC50:  60nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20328(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Affinity DataKi:  100nM ΔG°:  -41.6kJ/mole EC50:  860nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20326(3-[(4-tert-butylphenyl)methyl]-1-[1-(3-fluoro-4-me...)
Affinity DataKi:  339nM ΔG°:  -38.4kJ/mole EC50:  223nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20333(1-[(4-tert-butylphenyl)methyl]-3-[1-(4-methanesulf...)
Affinity DataKi:  370nM ΔG°:  -38.2kJ/mole EC50:  243nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20284(N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...)
Affinity DataKi:  1.30E+3nM ΔG°:  -34.9kJ/mole EC50:  520nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM20332(3-[(4-tert-butylphenyl)methyl]-1-[2-(4-methanesulf...)
Affinity DataKi:  2.89E+3nM ΔG°:  -32.9kJ/mole EC50:  663nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20327(3-[(4-tert-butylphenyl)methyl]-1-[1-(3-fluoro-4-me...)
Affinity DataKi:  1.74E+3nM ΔG°:  -34.2kJ/mole EC50:  700nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20329(3-[(4-tert-butylphenyl)methyl]-1-[2-(3-fluoro-4-me...)
Affinity DataKi:  7.70E+3nM ΔG°:  -30.4kJ/mole EC50:  980nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20319(3-[(4-tert-butylphenyl)methyl]-1-[2-(4-methanesulf...)
Affinity DataEC50:  1.80E+3nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20324(3-[(4-tert-butylphenyl)methyl]-1-[(1S)-1-(3-fluoro...)
Affinity DataKi:  2.14E+3nM ΔG°:  -33.7kJ/mole EC50:  2.67E+3nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM20318(3-[(4-tert-butylphenyl)methyl]-1-[(1S)-1-(4-methan...)
Affinity DataKi:  3.95E+3nM ΔG°:  -32.1kJ/molepH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed