Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 2579
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22266({ethyl[(3R)-1-[1-(4-fluorophenyl)ethyl]pyrrolidin-...)
Affinity DataIC50: 3nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22249(N-{2-[5-(4-methoxyphenyl)-2-(thiophen-2-yl)-1H-imi...)
Affinity DataIC50: 6nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22265({ethyl[(3R)-1-(2-phenylpropan-2-yl)pyrrolidin-3-yl...)
Affinity DataIC50: 10nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22264({[(3R)-1-(3,4-dichlorophenyl)pyrrolidin-3-yl](meth...)
Affinity DataIC50: 11nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22253(4-butyl-N-{2-[5-(4-methoxyphenyl)-2-(thiophen-2-yl...)
Affinity DataIC50: 14nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22230(N-{2-[5-(4-methoxyphenyl)-2-phenyl-1H-imidazol-4-y...)
Affinity DataIC50: 14nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22261({[(3R)-1-benzylpyrrolidin-3-yl](methyl)sulfamoyl}(...)
Affinity DataIC50: 31nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22232(N-[2-(2,5-diphenyl-1H-imidazol-4-yl)ethyl]-4-penty...)
Affinity DataIC50: 33nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22256(4-(3,4-dichlorophenyl)-N-{2-[5-(4-methoxyphenyl)-2...)
Affinity DataIC50: 36nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22263({[(3R)-1-benzylpyrrolidin-3-yl](methyl)sulfamoyl}(...)
Affinity DataIC50: 38nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22255(4-(2-chlorophenyl)-N-{2-[5-(4-methoxyphenyl)-2-(th...)
Affinity DataIC50: 45nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22251(N-{3-[5-(4-methoxyphenyl)-2-(thiophen-2-yl)-1H-imi...)
Affinity DataIC50: 53nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22257(4-(3,4-dichlorophenyl)-N-{2-[5-(4-methoxyphenyl)-2...)
Affinity DataIC50: 55nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22234(N-{2-[5-(4-fluorophenyl)-2-phenyl-1H-imidazol-4-yl...)
Affinity DataIC50: 59nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22233(4-pentyl-N-(2-{2-phenyl-5-[4-(trifluoromethyl)phen...)
Affinity DataIC50: 72nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22262({[(3S)-1-benzylpyrrolidin-3-yl](methyl)sulfamoyl}(...)
Affinity DataIC50: 80nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22235(N-{2-[5-(3-methoxyphenyl)-2-phenyl-1H-imidazol-4-y...)
Affinity DataIC50: 82nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22259({[(3R)-1-benzylpyrrolidin-3-yl]sulfamoyl}({2-[5-(4...)
Affinity DataIC50: 83nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22244(N-{2-[5-(4-methoxyphenyl)-2-(pyridin-4-yl)-1H-imid...)
Affinity DataIC50: 87nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22254(N-{2-[5-(4-methoxyphenyl)-2-(thiophen-2-yl)-1H-imi...)
Affinity DataIC50: 91nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22239(N-{2-[5-(4-methoxyphenyl)-2-(3-nitrophenyl)-1H-imi...)
Affinity DataIC50: 99nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22250(N-{3-[5-(4-methoxyphenyl)-2-phenyl-1H-imidazol-4-y...)
Affinity DataIC50: 140nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22238(N-{2-[2-(4-chlorophenyl)-5-(4-methoxyphenyl)-1H-im...)
Affinity DataIC50: 210nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22258(N-{2-[5-(4-methoxyphenyl)-2-phenyl-1H-imidazol-4-y...)
Affinity DataIC50: 212nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22260({[(3S)-1-benzylpyrrolidin-3-yl]sulfamoyl}({2-[5-(4...)
Affinity DataIC50: 272nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22252(N-{2-[5-(4-methoxyphenyl)-2-phenyl-1H-imidazol-4-y...)
Affinity DataIC50: 364nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22246(N-{2-[5-(4-methoxyphenyl)-2-(pyridin-3-yl)-1H-imid...)
Affinity DataIC50: 560nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22248(N-{2-[5-(4-methoxyphenyl)-2-(2-methyl-1,3-thiazol-...)
Affinity DataIC50: 720nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22245(N-{2-[5-(4-methoxyphenyl)-2-(pyridin-2-yl)-1H-imid...)
Affinity DataIC50: 970nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22243(N-{2-[2-tert-butyl-5-(4-methoxyphenyl)-1H-imidazol...)
Affinity DataIC50: 1.92E+3nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22247(N-{2-[5-(4-methoxyphenyl)-2-(pyrazin-2-yl)-1H-imid...)
Affinity DataIC50: 2.81E+3nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22237(N-{2-[5-(4-methoxyphenyl)-2-(4-methylphenyl)-1H-im...)
Affinity DataIC50: 3.00E+3nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22240(N-{2-[5-(4-methoxyphenyl)-1H-imidazol-4-yl]ethyl}-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22241(N-{2-[5-(4-methoxyphenyl)-2-methyl-1H-imidazol-4-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22242(N-{2-[2-cyclopropyl-5-(4-methoxyphenyl)-1H-imidazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22236(N-{2-[2,5-bis(4-methoxyphenyl)-1H-imidazol-4-yl]et...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed