Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 2608
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22577(CHEMBL277006 | 2-{1-[(4-chlorophenyl)carbonyl]-5-m...)
Affinity DataIC50: 85nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22572(CHEMBL24957 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22569(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 170nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22574(CHEMBL432260 | 2-{1-[(4-chlorophenyl)carbonyl]-5-m...)
Affinity DataIC50: 250nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22571(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 270nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22573(CHEMBL27784 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 280nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22573(CHEMBL27784 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 350nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22576(CHEMBL26509 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 440nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22571(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 590nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22575(CHEMBL281379 | 2-{1-[(4-chlorophenyl)carbonyl]-5-m...)
Affinity DataIC50: 1.00E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22577(CHEMBL277006 | 2-{1-[(4-chlorophenyl)carbonyl]-5-m...)
Affinity DataIC50: 1.30E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22575(CHEMBL281379 | 2-{1-[(4-chlorophenyl)carbonyl]-5-m...)
Affinity DataIC50: 2.30E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22569(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 3.30E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22576(CHEMBL26509 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 4.70E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22574(CHEMBL432260 | 2-{1-[(4-chlorophenyl)carbonyl]-5-m...)
Affinity DataIC50: 5.10E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22572(CHEMBL24957 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 5.90E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed