Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50025479
TargetSodium-dependent serotonin transporter(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(RTI 55, (exo,exo)-isomer, Iodine (125) labeled | R...)
Affinity DataKd:  0.880nMAssay Description:Displacement of [125I]beta-CIT from human SERT in human platelet plasma membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(RTI 55, (exo,exo)-isomer, Iodine (125) labeled | R...)
Affinity DataKd:  2.82nMAssay Description:Displacement of [125I]beta-CIT from human SERT in human platelet membrane in presence of 5 uM ibogaineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50206577(CHEMBL222287 | 10-methoxyibogamine | IBOGAINE)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [125I]beta-CIT from rat SERT expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50206577(CHEMBL222287 | 10-methoxyibogamine | IBOGAINE)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of [3H]5HT uptake at rat SERT expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed