Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50037959
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50179260(CHEMBL537177 | 1-(3-(6-methoxynaphthalen-1-yl)prop...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219753(1-cyclohexyl-4-[3-(7-methoxynaphthalen-1-yl)propyl...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50145022(CHEMBL535856 | PB-183 | 1-Cyclohexyl-4-[3-(5-metho...)
Affinity DataKi:  1.57nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219751(1-cyclohexyl-4-[3-(6-methoxynaphthalen-1-yl)propyl...)
Affinity DataKi:  3.16nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  3.24nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219749(3,3-dimethyl-1-[3-(7-methoxynaphthalen-1-yl)propyl...)
Affinity DataKi:  4.12nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50145022(CHEMBL535856 | PB-183 | 1-Cyclohexyl-4-[3-(5-metho...)
Affinity DataKi:  4.51nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219755(1-cyclohexyl-4-[3-(7-hydroxynaphthalen-1-yl)propyl...)
Affinity DataKi:  5.48nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219750(1-cyclohexyl-4-[3-(6-hydroxynaphthalen-1-yl)propyl...)
Affinity DataKi:  6.78nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219751(1-cyclohexyl-4-[3-(6-methoxynaphthalen-1-yl)propyl...)
Affinity DataKi:  7.06nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219747(3,3-dimethyl-1-[3-(5-methoxynaphthalen-1-yl)propyl...)
Affinity DataKi:  12.8nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219750(1-cyclohexyl-4-[3-(6-hydroxynaphthalen-1-yl)propyl...)
Affinity DataKi:  21.3nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219748(3,3-dimethyl-1-[5-(9H-carbazol-9-yl)pentyl]piperid...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219757(3,3-dimethyl-1-[3-(7-hydroxynaphthalen-1-yl)propyl...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219753(1-cyclohexyl-4-[3-(7-methoxynaphthalen-1-yl)propyl...)
Affinity DataKi:  42.4nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219747(3,3-dimethyl-1-[3-(5-methoxynaphthalen-1-yl)propyl...)
Affinity DataKi:  44.9nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219755(1-cyclohexyl-4-[3-(7-hydroxynaphthalen-1-yl)propyl...)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219754(1-cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperaz...)
Affinity DataKi:  79.9nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219749(3,3-dimethyl-1-[3-(7-methoxynaphthalen-1-yl)propyl...)
Affinity DataKi:  115nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219748(3,3-dimethyl-1-[5-(9H-carbazol-9-yl)pentyl]piperid...)
Affinity DataKi:  138nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219745(3,3-dimethyl-1-[4-(9H-carbazol-9-yl)butyl]piperidi...)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219745(3,3-dimethyl-1-[4-(9H-carbazol-9-yl)butyl]piperidi...)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219746(3,3-dimethyl-1-[3-(6-hydroxynaphthalen-1-yl)propyl...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219752(3,3-dimethyl-1-[3-(9H-carbazol-9-yl)propyl]piperid...)
Affinity DataKi:  345nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219746(3,3-dimethyl-1-[3-(6-hydroxynaphthalen-1-yl)propyl...)
Affinity DataKi:  352nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219757(3,3-dimethyl-1-[3-(7-hydroxynaphthalen-1-yl)propyl...)
Affinity DataKi:  733nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219752(3,3-dimethyl-1-[3-(9H-carbazol-9-yl)propyl]piperid...)
Affinity DataKi:  2.02E+3nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50219754(1-cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperaz...)
Affinity DataKi:  3.45E+3nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed