Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50021069
LigandPNGBDBM50220573(1-(1-(3-chloro-4-hydroxyphenyl)-1-hydroxypropan-2-...)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220589(6-(1-hydroxy-2-(4-hydroxy-4-(3-(phenoxymethyl)phen...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220583(6-(2-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 6.60nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220588(6-(1-hydroxy-2-(4-hydroxy-4-(3-methoxyphenyl)piper...)
Affinity DataIC50: 8.30nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220581(7-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 8.70nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220574(6-(1-hydroxy-2-(4-hydroxy-4-p-tolylpiperidin-1-yl)...)
Affinity DataIC50: 9.10nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220584(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 9.10nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220577(6-(2-(4-(3-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220576(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50032651(1-[(1S,2S)-2-Hydroxy-2-(4-hydroxy-phenyl)-1-methyl...)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220582(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220578(6-(2-(4-(3,4-dihydro-1H-isochromen-7-yl)-4-hydroxy...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220580(4-(4-fluorophenyl)-1-(1-hydroxy-1-(4-hydroxy-2-met...)
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220585(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220572(4-(4-fluorophenyl)-1-(1-hydroxy-1-(4-hydroxy-3-met...)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220587(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220575(4-(4-fluoro-phenyl)-1-[2-hydroxy-2-(6-hydroxy-biph...)
Affinity DataIC50: 570nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220581(7-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220585(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220587(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220582(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220574(6-(1-hydroxy-2-(4-hydroxy-4-p-tolylpiperidin-1-yl)...)
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220573(1-(1-(3-chloro-4-hydroxyphenyl)-1-hydroxypropan-2-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220580(4-(4-fluorophenyl)-1-(1-hydroxy-1-(4-hydroxy-2-met...)
Affinity DataIC50: 3.90E+3nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220579(1-(1-(3-tert-butyl-4-hydroxyphenyl)-1-hydroxypropa...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220584(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 7.40E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220575(4-(4-fluoro-phenyl)-1-[2-hydroxy-2-(6-hydroxy-biph...)
Affinity DataIC50: 8.40E+3nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220576(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 8.60E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 9.80E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50032651(1-[(1S,2S)-2-Hydroxy-2-(4-hydroxy-phenyl)-1-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220577(6-(2-(4-(3-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032651(1-[(1S,2S)-2-Hydroxy-2-(4-hydroxy-phenyl)-1-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220588(6-(1-hydroxy-2-(4-hydroxy-4-(3-methoxyphenyl)piper...)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220587(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220578(6-(2-(4-(3,4-dihydro-1H-isochromen-7-yl)-4-hydroxy...)
Affinity DataIC50: 1.60E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220581(7-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220584(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220585(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220582(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220576(6-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]bufuralol from CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed