Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50038040
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221567(CHEMBL245802 | Chk1_144 | 4-[5-(6,7-dimethoxy-2,4-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220753(CHEMBL398750 | 5-(6,7-dimethoxy-2,4-dihydro-indeno...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221587(4-[7-methoxy-6-(tetrahydro-pyran-4-yloxy)-2,4-dihy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214577(Chk1_115 | CHEMBL245796 | 4'-(6,7-dimethoxy-1,4-di...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221592(4-[7-methoxy-6-(tetrahydro-furan-3-yloxy)-2,4-dihy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221574(3-(6-fluoro-pyridin-3-yl)-6,7-dimethoxy-2,4-dihydr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221584(4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221575(4-(6-hydroxy-7-methoxy-2,4-dihydro-indeno[1,2-c]py...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221571(4-(6-imidazol-1-ylmethyl-7-methoxy-2,4-dihydro-ind...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221570(4-[7-methoxy-6-(3-morpholin-4-yl-propoxy)-2,4-dihy...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221569(4-[7-methoxy-6-(tetrahydro-furan-3-ylmethoxy)-2,4-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221591(4-[6-(2-hydroxy-1-hydroxymethyl-ethoxy)-7-methoxy-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221613(3-(4-cyano-phenyl)-7-methoxy-2,4-dihydro-indeno[1,...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221582(4-[6-(3-dimethylamino-propoxy)-7-methoxy-2,4-dihyd...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221609(3-(6-chloro-pyridin-3-yl)-6,7-dimethoxy-2,4-dihydr...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221589(CHEMBL248396 | Chk1_146 | 4-(6,7-dimethoxy-2,4-dih...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221606(3-(4-cyano-phenyl)-2,4-dihydro-indeno[1,2-c]pyrazo...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221577(4-[6-((R)-2,3-dihydroxy-propoxy)-7-methoxy-2,4-dih...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221593(4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzoni...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221599(4-{7-methoxy-6-[2-(5-methyl-thiazol-4-yl)-ethoxy]-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221595(4-[7-methoxy-6-(pyridin-2-ylmethoxy)-2,4-dihydro-i...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221585(CHEMBL245605 | Chk1_123 | 6,7-dimethoxy-3-[4-(2H-t...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221598(4-[7-methoxy-6-(pyridin-3-ylmethoxy)-2,4-dihydro-i...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221580(6,7-dimethoxy-3-pyridin-3-yl-2,4-dihydro-indeno[1,...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221614(3-(5,6-dichloro-pyridin-3-yl)-6,7-dimethoxy-2,4-di...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221581(4-{6-[(4-hydroxy-cyclohexylamino)-methyl]-7-methox...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221583(4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221620(4-[7-methoxy-6-(pyridin-4-ylmethoxy)-2,4-dihydro-i...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221568([4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221607(CHEMBL401274 | Chk1_4 | 4-(6,7-dimethoxy-2,4-dihyd...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221602(6-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221576(6,7-dimethoxy-3-pyrimidin-5-yl-2,4-dihydro-indeno[...)
Affinity DataIC50: 44nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221586(6,7-dimethoxy-3-[4-(1H-pyrazol-4-yl)-phenyl]-2,4-d...)
Affinity DataIC50: 47nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221579(3-(4-bromo-phenyl)-6,7-dimethoxy-2,4-dihydro-inden...)
Affinity DataIC50: 73nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221597(4-{6-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-7-methoxy-2...)
Affinity DataIC50: 77nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221588(6,7-dimethoxy-3-[4-(1H-pyrrol-2-yl)-phenyl]-2,4-di...)
Affinity DataIC50: 77nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221572(6,7-dimethoxy-3-pyrazin-2-yl-2,4-dihydro-indeno[1,...)
Affinity DataIC50: 89nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221617(6,7-dimethoxy-3-(6-trifluoromethyl-pyridin-3-yl)-2...)
Affinity DataIC50: 288nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221616(3-(6-bromo-pyridin-3-yl)-6,7-dimethoxy-2,4-dihydro...)
Affinity DataIC50: 288nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221590(4'-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol...)
Affinity DataIC50: 355nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221608(4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol-...)
Affinity DataIC50: 779nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221605(3-[4-(1H-imidazol-4-yl)-phenyl]-6,7-dimethoxy-2,4-...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221618([4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221619(6,7-dimethoxy-3-[4-(1-methyl-3H-imidazol-4-yl)-phe...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221603(4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol-...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221596(5-[4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyraz...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221601(6,7-dimethoxy-3-[4-(3-methyl-3H-imidazol-4-yl)-phe...)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221604(1-[4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyraz...)
Affinity DataIC50: 4.58E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221612(3-ethynyl-6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]p...)
Affinity DataIC50: 5.14E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50221573(6,7-dimethoxy-3-(4-morpholin-4-yl-phenyl)-2,4-dihy...)
Affinity DataIC50: 6.22E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
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