Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021196
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50221986(H-Tyr-Pro-Phe-Phe-NH-CH2-CH2-NH Tic Dmt-H | CHEMBL...)
Affinity DataKi:  1.03nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50221986(H-Tyr-Pro-Phe-Phe-NH-CH2-CH2-NH Tic Dmt-H | CHEMBL...)
Affinity DataKi:  1.45nMAssay Description:Displacement of [3H]deltorphin 2 from delta-opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50221985(H-Dmt-Tic-NH-CH2-CH2-NH2 | CHEMBL241010)
Affinity DataKi:  1.81nMAssay Description:Displacement of [3H]deltorphin 2 from delta-opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50221985(H-Dmt-Tic-NH-CH2-CH2-NH2 | CHEMBL241010)
Affinity DataKi:  2.72nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50221986(H-Tyr-Pro-Phe-Phe-NH-CH2-CH2-NH Tic Dmt-H | CHEMBL...)
Affinity DataIC50: 25.1nMAssay Description:Agonist activity at mu-opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50221985(H-Dmt-Tic-NH-CH2-CH2-NH2 | CHEMBL241010)
Affinity DataIC50: 286nMAssay Description:Agonist activity at mu-opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed