Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50021207
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222063((R,E)-2-(5-chlorothiophen-2-yl)-N-((1-(1-(pyridin-...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222062((E)-2-(5-(5-chlorothiophen-2-yl)thiophen-2-yl)-N-(...)
Affinity DataIC50: 18nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222078((R,E)-2-(5-bromothiophen-2-yl)-N-((1-(1-(pyridin-4...)
Affinity DataIC50: 22nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222065(5-(5-chlorothiophen-2-yl)-N-(((S)-1-((S)-2-(pyrrol...)
Affinity DataIC50: 40nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222077(5-(5-chlorothiophen-2-yl)-N-(((R)-1-(1-(2-methylpy...)
Affinity DataIC50: 61nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222072((E)-2-(5-chlorothiophen-2-yl)-N-(((S)-1-(2-oxo-2-(...)
Affinity DataIC50: 70nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222064((E)-2-(5-bromothiophen-2-yl)-N-((1-(1-(pyridin-4-y...)
Affinity DataIC50: 86nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222079(5-(5-chlorothiophen-2-yl)-N-(((S)-1-(pyrrolidine-1...)
Affinity DataIC50: 130nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222069((S,E)-2-(5-chlorothiophen-2-yl)-N-((1-(1-(pyridin-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222071((R,E)-2-(5-chlorothiophen-2-yl)-N-((1-(1-(2-methyl...)
Affinity DataIC50: 230nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222070(6-chloro-N-((1-(1-(pyridin-4-yl)piperidine-4-carbo...)
Affinity DataIC50: 247nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222068(6-chloro-N-((1-(1-(pyridin-4-yl)piperidine-4-carbo...)
Affinity DataIC50: 255nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222080((E)-2-(5-chlorothiophen-2-yl)-N-(((R)-1-(2-oxo-2-(...)
Affinity DataIC50: 436nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222066((E)-2-(4-chlorophenyl)-N-((1-(1-(pyridin-4-yl)pipe...)
Affinity DataIC50: 493nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222073((S,E)-2-(5-chlorothiophen-2-yl)-N-((1-(1-(2-methyl...)
Affinity DataIC50: 718nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222067(N-((1-(1-(pyridin-4-yl)piperidine-4-carbonyl)pyrro...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222076((S,E)-N-((1-(4-(1H-imidazol-1-yl)benzoyl)pyrrolidi...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222062((E)-2-(5-(5-chlorothiophen-2-yl)thiophen-2-yl)-N-(...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222074(4'-((R)-3-{[(E)-2-(5-chloro-thiophen-2-yl)-ethenes...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222062((E)-2-(5-(5-chlorothiophen-2-yl)thiophen-2-yl)-N-(...)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222062((E)-2-(5-(5-chlorothiophen-2-yl)thiophen-2-yl)-N-(...)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222075((E)-2-(3-chlorophenyl)-N-((1-(1-(pyridin-4-yl)pipe...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222062((E)-2-(5-(5-chlorothiophen-2-yl)thiophen-2-yl)-N-(...)
Affinity DataIC50: 7.97E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222062((E)-2-(5-(5-chlorothiophen-2-yl)thiophen-2-yl)-N-(...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50222062((E)-2-(5-(5-chlorothiophen-2-yl)thiophen-2-yl)-N-(...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed