Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50025556
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataKi:  0.550nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242403([3,5-Dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phe...)
Affinity DataKi:  2.17nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  7.18nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242403([3,5-Dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phe...)
Affinity DataKi:  35.2nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242404(MB-07811 | (4S)-4-(3-chlorophenyl)-2-[(3,5-dimethy...)
Affinity DataKi:  1.25E+4nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242404(MB-07811 | (4S)-4-(3-chlorophenyl)-2-[(3,5-dimethy...)
Affinity DataKi:  1.46E+4nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed