Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50021306
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223140(N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223136(N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216671(tert-butyl (R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-te...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223139(tert-butyl (R)-1-((R)-5-isopropyl-4-oxo-2,3,4,5-te...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223150(tert-butyl (R)-1-(9-isopropyl-8-oxo-6,7,8,9-tetrah...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223153(4-fluoro-N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 94nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223146(N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50: 98nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223145(N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 107nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223137(tert-butyl (R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2...)
Affinity DataIC50: 108nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223147(4-fluoro-N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 128nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223138(N-[(R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50: 131nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223154(N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 146nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223156(N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 169nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223142(N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223148(N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50: 177nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223152(3,3,3-trifluoro-N-[(R)-1-((R)-1-isopropyl-2-oxo-2,...)
Affinity DataIC50: 203nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223135(N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 232nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223155(N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223141(N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50: 453nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223151((R)-N-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro-1H...)
Affinity DataIC50: 868nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223143(N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223134(N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223149(N-((R)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223144((R)-2-acetamido-N-((R)-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed