Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50038393
TargetVitamin D3 receptor(Rat)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  0.100nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from rat recombinant His-tagged VDR ligand-binding domain expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Rat)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292629((23S)-25-dehydro-2-methylene-19-nor-1alpha-hydroxy...)
Affinity DataEC50:  0.700nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from rat recombinant His-tagged VDR ligand-binding domain expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292629((23S)-25-dehydro-2-methylene-19-nor-1alpha-hydroxy...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Rat)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375809(CHEMBL429347)
Affinity DataEC50:  5nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from rat recombinant His-tagged VDR ligand-binding domain expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Rat)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375808(CHEMBL409470)
Affinity DataEC50:  5nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from rat recombinant His-tagged VDR ligand-binding domain expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375809(CHEMBL429347)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375808(CHEMBL409470)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375808(CHEMBL409470)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375809(CHEMBL429347)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Rat)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292630((5R)-5-{(2R)-2-[(1R,3R,7E)-1,3-Dihydroxy-2-methyle...)
Affinity DataEC50:  20nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from rat recombinant His-tagged VDR ligand-binding domain expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292629((23S)-25-dehydro-2-methylene-19-nor-1alpha-hydroxy...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375808(CHEMBL409470)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292630((5R)-5-{(2R)-2-[(1R,3R,7E)-1,3-Dihydroxy-2-methyle...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292630((5R)-5-{(2R)-2-[(1R,3R,7E)-1,3-Dihydroxy-2-methyle...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292629((23S)-25-dehydro-2-methylene-19-nor-1alpha-hydroxy...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375809(CHEMBL429347)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292630((5R)-5-{(2R)-2-[(1R,3R,7E)-1,3-Dihydroxy-2-methyle...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50292630((5R)-5-{(2R)-2-[(1R,3R,7E)-1,3-Dihydroxy-2-methyle...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed