Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 50021359
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223698(5-cyano-N-(5-hydroxy-2-(piperidin-1-yl)phenyl)fura...)
Affinity DataIC50: 17nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223693(5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-ca...)
Affinity DataIC50: 17nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223670(5-cyano-N-(5-((2,3-dihydroxypropoxy)methyl)-2-(pip...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM17750(5-cyano-N-[5-(hydroxymethyl)-2-(4-methylpiperidin-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223700(5-cyano-N-(5-(hydroxymethyl)-2-(piperidin-1-yl)phe...)
Affinity DataIC50: 25nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223680(5-cyano-furan-2-carboxylic acid (5-guanidinomethyl...)
Affinity DataIC50: 34nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223699(5-cyano-N-(2-(piperidin-1-yl)phenyl)furan-2-carbox...)
Affinity DataIC50: 36nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223681(5-cyano-N-(5-(methylsulfonamidomethyl)-2-(piperidi...)
Affinity DataIC50: 37nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223674(5-cyano-N-(5-formyl-2-(piperidin-1-yl)phenyl)furan...)
Affinity DataIC50: 37nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223706(N-(2-(4-(2-hydroxyethyl)piperidin-1-yl)phenyl)-5-n...)
Affinity DataIC50: 43nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223665(4-cyano-N-(2-(piperidin-1-yl)phenyl)-1H-pyrrole-2-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223701(4-nitro-N-(2-(piperidin-1-yl)phenyl)-1H-pyrrole-2-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223683(5-nitro-N-(2-(piperidin-1-yl)phenyl)furan-2-carbox...)
Affinity DataIC50: 53nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223693(5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-ca...)
Affinity DataIC50: 76nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223668(N-(2-(4-methylpiperidin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223682(5-cyano-N-(5-((4-methylpiperazin-1-yl)methyl)-2-(p...)
Affinity DataIC50: 80nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223686(5-cyano-N-(5-methoxy-2-(piperidin-1-yl)phenyl)fura...)
Affinity DataIC50: 90nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223685(5-cyano-N-(5-cyano-2-(piperidin-1-yl)phenyl)furan-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223676(N-(2-(4-(hydroxymethyl)piperidin-1-yl)phenyl)-5-ni...)
Affinity DataIC50: 130nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223688(N-(2-(4-hydroxypiperidin-1-yl)phenyl)-5-nitrofuran...)
Affinity DataIC50: 140nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223665(4-cyano-N-(2-(piperidin-1-yl)phenyl)-1H-pyrrole-2-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223670(5-cyano-N-(5-((2,3-dihydroxypropoxy)methyl)-2-(pip...)
Affinity DataIC50: 170nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223701(4-nitro-N-(2-(piperidin-1-yl)phenyl)-1H-pyrrole-2-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223700(5-cyano-N-(5-(hydroxymethyl)-2-(piperidin-1-yl)phe...)
Affinity DataIC50: 190nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223697(N-(5-(aminomethyl)-2-(piperidin-1-yl)phenyl)-5-cya...)
Affinity DataIC50: 200nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223706(N-(2-(4-(2-hydroxyethyl)piperidin-1-yl)phenyl)-5-n...)
Affinity DataIC50: 230nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM17750(5-cyano-N-[5-(hydroxymethyl)-2-(4-methylpiperidin-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223672(N-(2-((2Z,4Z,6Z)-1H-azepin-1-yl)phenyl)-5-nitrofur...)
Affinity DataIC50: 260nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223668(N-(2-(4-methylpiperidin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223681(5-cyano-N-(5-(methylsulfonamidomethyl)-2-(piperidi...)
Affinity DataIC50: 310nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223674(5-cyano-N-(5-formyl-2-(piperidin-1-yl)phenyl)furan...)
Affinity DataIC50: 330nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223683(5-nitro-N-(2-(piperidin-1-yl)phenyl)furan-2-carbox...)
Affinity DataIC50: 360nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223688(N-(2-(4-hydroxypiperidin-1-yl)phenyl)-5-nitrofuran...)
Affinity DataIC50: 370nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223699(5-cyano-N-(2-(piperidin-1-yl)phenyl)furan-2-carbox...)
Affinity DataIC50: 370nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223677(N-(2-(3-methylpiperidin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 380nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223669(N-(2-(4-methylpiperazin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 390nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223708(N-(2-(2-methylpiperidin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 720nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223685(5-cyano-N-(5-cyano-2-(piperidin-1-yl)phenyl)furan-...)
Affinity DataIC50: 750nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223686(5-cyano-N-(5-methoxy-2-(piperidin-1-yl)phenyl)fura...)
Affinity DataIC50: 960nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223682(5-cyano-N-(5-((4-methylpiperazin-1-yl)methyl)-2-(p...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223667(5-formyl-N-(2-(piperidin-1-yl)phenyl)furan-2-carbo...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223675(cid_2996093 | CHEMBL251369 | N-(2-morpholinophenyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223676(N-(2-(4-(hydroxymethyl)piperidin-1-yl)phenyl)-5-ni...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223669(N-(2-(4-methylpiperazin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223694(5-chloro-N-(2-(piperidin-1-yl)phenyl)furan-2-carbo...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223673(CHEMBL249987 | cid_2996559 | 5-nitro-N-(2-(pyrroli...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223692(3-(2-cyanofuran-5-carboxamido)-4-(piperidin-1-yl)b...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223692(3-(2-cyanofuran-5-carboxamido)-4-(piperidin-1-yl)b...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223672(N-(2-((2Z,4Z,6Z)-1H-azepin-1-yl)phenyl)-5-nitrofur...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223677(N-(2-(3-methylpiperidin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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