Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50041660
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128063(CHEMBL67133 | CHEMBL112210 | Allyl-{6-[3-(4-bromo-...)
Affinity DataIC50: 2.88nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128054(N-allyl-6-(1-(4-bromophenyl)isoquinolin-6-yloxy)-N...)
Affinity DataIC50: 3.47nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128055(CHEMBL66638 | CHEMBL115085 | Allyl-{6-[4-(4-bromo-...)
Affinity DataIC50: 4.07nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128050(CHEMBL114259 | CHEMBL416694 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50: 5.37nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128072({4-[((1S,2S)-2-{[ALLYL(CYCLOPROPYL)AMINO]METHYL}CY...)
Affinity DataIC50: 6.46nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128064(N-allyl-4-(3-(4-bromophenyl)benzo[b]thiophen-6-ylo...)
Affinity DataIC50: 13.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128062(CHEMBL62855 | (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPRO...)
Affinity DataIC50: 19.1nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50412870(CHEMBL612028)
Affinity DataIC50: 19.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128061(N-(((1S,2S)-2-((4-(4-bromobenzoyl)phenoxy)methyl)c...)
Affinity DataIC50: 21.9nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128046(N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6-ylo...)
Affinity DataIC50: 28.8nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50130777(CHEMBL114910 | CHEMBL611487 | (4-Bromo-phenyl)-(4-...)
Affinity DataIC50: 28.8nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128051(N-allyl-6-(3-(4-bromophenyl)-1H-indazol-6-yloxy)-N...)
Affinity DataIC50: 38.9nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128057(N-(6-(1-(4-fluorobenzoyl)piperidin-4-yloxy)hexyl)-...)
Affinity DataIC50: 47.9nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128059(N-allyl-6-(1-(4-fluorobenzoyl)piperidin-4-yloxy)-N...)
Affinity DataIC50: 70.8nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128048(N-(6-(4-(4-bromobenzoyl)-3-fluorophenoxy)hexyl)-N-...)
Affinity DataIC50: 97.7nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128065({4-[6-(Allyl-methyl-amino)-hexyloxy]-2-fluoro-phen...)
Affinity DataIC50: 224nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50412870(CHEMBL612028)
Affinity DataIC50: 240nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128069(N-(((1S,2S)-2-((4-(4-bromobenzoyl)-3-fluorophenoxy...)
Affinity DataIC50: 437nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128056(CHEMBL481811 | CHEMBL65553 | ALLYL-{4-[3-(4-BROMO-...)
Affinity DataIC50: 501nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128045(Allyl-{6-[3-(4-bromo-phenyl)-benzofuran-6-yloxy]-h...)
Affinity DataIC50: 617nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128047(N-allyl-4-(4-(6-bromobenzo[d]isothiazol-3-yl)pheno...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128052(Allyl-{6-[4-(6-bromo-benzo[d]isothiazol-3-yl)-phen...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed