Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50021652
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226460(12-O-deacetyl-12-epi-19-deoxy-21-hydroxyscalarin |...)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226461(12-O-deacetyl-12-epi-19-O-methylscalarin | CHEMBL2...)
Affinity DataIC50: 2.40E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226463(12-deacetyl-12-epi-19-deoxyscalarin | 12-O-deacety...)
Affinity DataIC50: 3.16E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226462(12-epi-scalarin | 12-Episcalarin | CHEMBL269105)
Affinity DataIC50: 6.04E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226459(12-O-deacetyl-12-epi-scalarin | CHEMBL399743)
Affinity DataIC50: 7.50E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226464(12-O-deacetyl-12-epi-19-deoxy-22-hydroxyscalarin |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed