Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50037998
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 500nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226637(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226637(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226646(4-chlorophenyl 3-(2-{[(3-hydroxypropyl)sulfonyl]am...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226646(4-chlorophenyl 3-(2-{[(3-hydroxypropyl)sulfonyl]am...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112552(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226641(N-[2,2-dimethyl-3-(nitrooxy)propyl]-2-{1-[(4-chlor...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226643(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226656(N-{1,1-bis[(nitrooxy)methyl]-2-(nitrooxy)ethyl}-2-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226639(N-(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-met...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226653(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112548(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226654(4-chlorophenyl 5-methoxy-2-methyl-3-{2-[({4-[(nitr...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226648(4-chlorophenyl 3-(2-hydroxyethyl)-5-methoxy-2-meth...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112552(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226641(N-[2,2-dimethyl-3-(nitrooxy)propyl]-2-{1-[(4-chlor...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226655(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226638(N-(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-met...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112548(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226657(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226647((2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methy...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226646(4-chlorophenyl 3-(2-{[(3-hydroxypropyl)sulfonyl]am...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226646(4-chlorophenyl 3-(2-{[(3-hydroxypropyl)sulfonyl]am...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226653(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226657(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50029074(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226655(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226644(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226643(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226659(3-(2-aminoethyl)-5-methoxy-2-methylindolyl 4-chlor...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226642(4-chlorophenyl 5-methoxy-2-methyl-3-[2-(nitrooxy)e...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226638(N-(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50029074(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226644(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226645(1-[(4-chlorophenyl)carbonyl]-2-methyl-3-({N-[3-(ni...)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226645(1-[(4-chlorophenyl)carbonyl]-2-methyl-3-({N-[3-(ni...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226658(phenylmethyl 2-{4-chloro-1-[(4-chlorophenyl)carbon...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226660((2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226640(phenylmethyl 2-{6-chloro-1-[(4-chlorophenyl)carbon...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226649((2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed