Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50021767
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227724(N-hydroxy-2-methyl-2-{4-[2-methyl-3'-(2-methylamin...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227723(2-{4-[3'-(2-amino-ethoxy)-2-methyl-biphenyl-4-yl]-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227725(2-{4-[3'-(2-dimethylamino-ethoxy)-2-methyl-bipheny...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(N-hydroxy-2-{4-[3'-(2-hydroxy-ethoxy)-2-methyl-bip...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227711(2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-piperidine...)
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227728(2-[4-(2-fluoro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227733(N-hydroxy-2-[4-(3'-methoxymethyl-2-methyl-biphenyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227717(N-hydroxy-2-{4-[3'-(2-methoxy-ethoxy)-2-methyl-bip...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227721(2-[4-(2,3'-dimethyl-biphenyl-4-yl)-3,6-dihydro-2H-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227710(2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydr...)
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227734(N-hydroxy-2-[4-(3'-methoxy-2-methyl-biphenyl-4-yl)...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227715(2-(4-biphenyl-4-yl-3,6-dihydro-2H-pyridine-1-sulfo...)
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227715(2-(4-biphenyl-4-yl-3,6-dihydro-2H-pyridine-1-sulfo...)
Affinity DataIC50: 9nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227719(N-hydroxy-2-[4-(2-methyl-biphenyl-4-yl)-3,6-dihydr...)
Affinity DataIC50: 16nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227728(2-[4-(2-fluoro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 17nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227714(2-(4-biphenyl-4-yl-piperidine-1-sulfonyl)-N-hydrox...)
Affinity DataIC50: 26nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227727(2-[4-(3'-ethyl-2-methyl-biphenyl-4-yl)-3,6-dihydro...)
Affinity DataIC50: 31nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227730(N-hydroxy-2-[4-(2-methyl-3'-trifluoromethoxy-biphe...)
Affinity DataIC50: 51nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227716(2-[4-(2-chloro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 55nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227732(2-[3-(biphenyl-4-yloxy)-azetidine-1-sulfonyl]-N-hy...)
Affinity DataIC50: 84nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227731(2-(3-biphenyl-4-yl-azetidine-1-sulfonyl)-N-hydroxy...)
Affinity DataIC50: 161nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227726(2-[(2-biphenyl-4-yl-ethyl)-methyl-sulfamoyl]-N-hyd...)
Affinity DataIC50: 164nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227730(N-hydroxy-2-[4-(2-methyl-3'-trifluoromethoxy-biphe...)
Affinity DataIC50: 173nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227720(2-[(3-biphenyl-4-yl-propyl)-methyl-sulfamoyl]-N-hy...)
Affinity DataIC50: 174nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227723(2-{4-[3'-(2-amino-ethoxy)-2-methyl-biphenyl-4-yl]-...)
Affinity DataIC50: 188nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227724(N-hydroxy-2-methyl-2-{4-[2-methyl-3'-(2-methylamin...)
Affinity DataIC50: 196nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227733(N-hydroxy-2-[4-(3'-methoxymethyl-2-methyl-biphenyl...)
Affinity DataIC50: 196nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227729(N-hydroxy-2-(4-(4-phenoxyphenyl)piperidin-1-ylsulf...)
Affinity DataIC50: 205nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227734(N-hydroxy-2-[4-(3'-methoxy-2-methyl-biphenyl-4-yl)...)
Affinity DataIC50: 222nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(N-hydroxy-2-{4-[3'-(2-hydroxy-ethoxy)-2-methyl-bip...)
Affinity DataIC50: 262nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227719(N-hydroxy-2-[4-(2-methyl-biphenyl-4-yl)-3,6-dihydr...)
Affinity DataIC50: 320nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227735(2-(biphenyl-4-ylmethyl-methyl-sulfamoyl)-N-hydroxy...)
Affinity DataIC50: 378nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(N-hydroxy-2-{4-[3'-(2-hydroxy-ethoxy)-2-methyl-bip...)
Affinity DataIC50: 406nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227713(2-[4-(2-ethyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridi...)
Affinity DataIC50: 420nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227711(2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-piperidine...)
Affinity DataIC50: 457nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 529nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227725(2-{4-[3'-(2-dimethylamino-ethoxy)-2-methyl-bipheny...)
Affinity DataIC50: 534nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227716(2-[4-(2-chloro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 620nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227721(2-[4-(2,3'-dimethyl-biphenyl-4-yl)-3,6-dihydro-2H-...)
Affinity DataIC50: 776nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227717(N-hydroxy-2-{4-[3'-(2-methoxy-ethoxy)-2-methyl-bip...)
Affinity DataIC50: 853nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227712(N-hydroxy-2-[4-(2-trifluoromethyl-biphenyl-4-yl)-3...)
Affinity DataIC50: 960nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227710(2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydr...)
Affinity DataIC50: 998nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227727(2-[4-(3'-ethyl-2-methyl-biphenyl-4-yl)-3,6-dihydro...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(N-hydroxy-2-{4-[3'-(2-hydroxy-ethoxy)-2-methyl-bip...)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227712(N-hydroxy-2-[4-(2-trifluoromethyl-biphenyl-4-yl)-3...)
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227722(N-hydroxy-2-{4-[3'-(2-hydroxy-ethoxy)-2-methyl-bip...)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
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