Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50021959
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  8.53nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229776(6-[(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)(pr...)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229775((-)-6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataEC50:  2.22nMAssay Description:Agonist activity at human cloned dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109926(7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-propyl-amin...)
Affinity DataEC50:  12.2nMAssay Description:Agonist activity at human cloned dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109926(7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-propyl-amin...)
Affinity DataEC50:  0.690nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229775((-)-6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229776(6-[(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)(pr...)
Affinity DataEC50:  1.56nMAssay Description:Agonist activity at human cloned dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  209nMAssay Description:Agonist activity at human cloned dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229783(6-[(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229776(6-[(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)(pr...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229776(6-[(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)(pr...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229775((-)-6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229775((-)-6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229775((-)-6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229778(6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]...)
Affinity DataKi:  1.39nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109926(7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-propyl-amin...)
Affinity DataKi:  1.56nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  2.35nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229776(6-[(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)(pr...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229782(6-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)amino]...)
Affinity DataKi:  2.89nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229776(6-[(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)(pr...)
Affinity DataKi:  9.56nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229776(6-[(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)(pr...)
Affinity DataKi:  9.56nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229780(7-[(3-(4-phenylpiperazin-1-yl)propyl)(propyl)amino...)
Affinity DataKi:  10.3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229784(8-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]...)
Affinity DataKi:  10.9nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229779(6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]...)
Affinity DataKi:  11.2nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229783(6-[(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)...)
Affinity DataKi:  14.6nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  19.3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  19.4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229782(6-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)amino]...)
Affinity DataKi:  21.7nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229781(N2-[2-(4-phenylpiperazin-1-yl)ethyl]-N2-propyl-1,2...)
Affinity DataKi:  22.2nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229777(7-[(2-(4-phenylpiperazin-1-yl)ethyl)(2-(thiophen-2...)
Affinity DataKi:  23.9nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229777(7-[(2-(4-phenylpiperazin-1-yl)ethyl)(2-(thiophen-2...)
Affinity DataKi:  24.6nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229775((-)-6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229775((-)-6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  32.9nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  32.9nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229776(6-[(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)(pr...)
Affinity DataKi:  35.8nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229778(6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]...)
Affinity DataKi:  70.3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229784(8-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]...)
Affinity DataKi:  90.6nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109926(7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-propyl-amin...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229780(7-[(3-(4-phenylpiperazin-1-yl)propyl)(propyl)amino...)
Affinity DataKi:  167nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229775((-)-6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)am...)
Affinity DataKi:  238nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229781(N2-[2-(4-phenylpiperazin-1-yl)ethyl]-N2-propyl-1,2...)
Affinity DataKi:  638nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50229779(6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]...)
Affinity DataKi:  649nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed