Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50038068
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231741(2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one | CH...)
Affinity DataEC50:  34nMAssay Description:Antagonist activity at mGluR5 in Sprague-Dawley rat astrocyte assessed as L-quisqualate induced potentiation of intracellular calcium level by FLIPR ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231741(2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one | CH...)
Affinity DataEC50:  172nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as L-glutamate induced potentiation of intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231747((R)-2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-...)
Affinity DataEC50:  180nMAssay Description:Antagonist activity at mGluR5 in Sprague-Dawley rat astrocyte assessed as L-quisqualate induced potentiation of intracellular calcium level by FLIPR ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231719(2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-ol |...)
Affinity DataEC50:  490nMAssay Description:Antagonist activity at mGluR5 in Sprague-Dawley rat astrocyte assessed as L-quisqualate induced potentiation of intracellular calcium level by FLIPR ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231759((S)-2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-...)
Affinity DataEC50:  250nMAssay Description:Antagonist activity at mGluR5 in Sprague-Dawley rat astrocyte assessed as L-quisqualate induced potentiation of intracellular calcium level by FLIPR ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231747((R)-2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-...)
Affinity DataEC50:  980nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as L-glutamate induced potentiation of intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231719(2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-ol |...)
Affinity DataEC50:  1.13E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as L-glutamate induced potentiation of intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231759((S)-2-phenylethynyl-5,6,7,8-tetrahydro-quinolin-5-...)
Affinity DataEC50:  1.08E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as L-glutamate induced potentiation of intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231750((3-ethyl-2-methylquinolin-6-yl)(4-methoxycyclohexy...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231744(NPS 2390 | CHEMBL399160 | quinoxaline-2-carboxylic...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231749(6-ethyl-5-methyl-3-(1,2,4,5-tetrahydrobenzo[d]azep...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231755(6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...)
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231748(quinoline-3-carboxylic acid adamantan-1-ylamide | ...)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231758(2-cyclopentylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetr...)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231728(5-methoxy-2-phenylethynyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231757(2-[4-(4-fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231743(7,7-dimethyl-5-oxo-2-(4-phenyl-piperazin-1-yl)-5,6...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231764(2-[4-(4-fluoro-phenyl)-piperazin-1-yl]-7,7-dimethy...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231752(quinoline-2-carboxylic acid adamantan-1-ylamide | ...)
Affinity DataIC50: 440nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231753(2-phenylethynyl-5,6,7,8-tetrahydro-quinoline | CHE...)
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50003013(CHEMBL401270)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231742(2-(3,4-dihydro-1H-isoquinolin-2-yl)-7,7-dimethyl-5...)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231736(2-butylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro...)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231735(2-(indan-2-ylamino)-7,7-dimethyl-5-oxo-5,6,7,8-tet...)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231740(2-benzyloxy-7,8-dihydro-6H-quinolin-5-one | CHEMBL...)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231733(7,7-dimethyl-5-oxo-2-propylamino-5,6,7,8-tetrahydr...)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231720(2-benzylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydr...)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231722(2-hexylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro...)
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231738(7,7-dimethyl-2-pyridin-2-ylethynyl-7,8-dihydro-6H-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231730(2-cyclohexylamino-5-oxo-5,6,7,8-tetrahydroquinolin...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231756(2-cyclohexylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetra...)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231751(6-phenylethynyl-nicotinic acid methyl ester | CHEM...)
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231723(2-benzylsulfanyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrah...)
Affinity DataIC50: 4.80E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231760(2-(benzyl-methyl-amino)-7,7-dimethyl-5-oxo-5,6,7,8...)
Affinity DataIC50: 5.30E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231727(cid_2931812 | CHEMBL253348 | pyrazine-2-carboxylic...)
Affinity DataIC50: 7.00E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231731(2-azepanyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-car...)
Affinity DataIC50: 7.40E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231746(2-[4-(4-methoxy-phenyl)-piperazin-1-yl]-7,7-dimeth...)
Affinity DataIC50: 7.60E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231724(3-chloro-2-cyclopentylamino-7,7-dimethyl-7,8-dihyd...)
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231729(2-benzylamino-7,7-dimethyl-7,8-dihydro-6H-quinolin...)
Affinity DataIC50: 8.10E+3nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231739(2-(4-phenyl-piperazin-1-yl)-7,8-dihydro-6H-quinoli...)
Affinity DataIC50: 1.04E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50371237(CHEMBL1204390)
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231732(7,7-dimethyl-3-nitro-2-(4-phenyl-3,6-dihydro-2H-py...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231765(2-(cyclopentylamino)-7,7-dimethyl-3-(2H-tetrazol-5...)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231766(2-[4-(4-fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...)
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231725(2-cyclopentylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetr...)
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50371237(CHEMBL1204390)
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231763(2-cyclopentylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetr...)
Affinity DataIC50: 2.30E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231740(2-benzyloxy-7,8-dihydro-6H-quinolin-5-one | CHEMBL...)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231745(2-(benzyl-methyl-amino)-5-oxo-5,6,7,8-tetrahydroqu...)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231761(3-bromo-2-cyclopentylamino-7,7-dimethyl-7,8-dihydr...)
Affinity DataIC50: 2.90E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 71 total ) | Next | Last >>
Jump to: