Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 3000
LigandPNGBDBM26789(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26791(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-({4-[(2-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26807((3R,4S)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26793(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26795(N-[(1R,2S)-2-(hydroxycarbamoyl)cyclopentyl]-4-{[2-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26802((5R,7R,8S)-7-N-(4-{[2-(2-fluoropropan-2-yl)-1H-1,3...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26799((5R,7S,8R)-7-N-hydroxy-8-N-(4-{[2-(propan-2-yl)-1H...)
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26800((5R,7R,8S)-7-N-{4-[(2-cyclopropyl-1H-1,3-benzodiaz...)
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26806((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...)
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26790((3S,4S)-3-N-hydroxy-4-N-(4-{[2-(methylsulfanyl)-1H...)
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26803((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(propan-2-yl)-1H-1,...)
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26794((3S,4S)-3-N-hydroxy-4-N-(4-{[2-(propan-2-yl)-1H-1,...)
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26797((3S,4S)-3-N-hydroxy-1-(prop-2-yn-1-yl)-4-N-(4-{[2-...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26801((5R,7R,8S)-7-N-{4-[(2-tert-butyl-1H-1,3-benzodiazo...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26804((3R,4R)-4-N-(4-{[2-(2-fluoropropan-2-yl)-1H-1,3-be...)
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26798((3S,4S)-3-N-{4-[(2-tert-butyl-1H-1,3-benzodiazol-1...)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26805((3R,4R)-4-N-(4-{[2-(1,1-difluoroethyl)-1H-1,3-benz...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26792((3S,4S)-3-N-hydroxy-4-N-{4-[(2-methyl-1H-1,3-benzo...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
LigandPNGBDBM26796(4-[(2-cyclopropyl-1H-1,3-benzodiazol-1-yl)methyl]-...)
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Bristol-Myers Squibb

LigandPNGBDBM26791(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-({4-[(2-...)
Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Bristol-Myers Squibb

LigandPNGBDBM26793(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataIC50: 390nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Bristol-Myers Squibb

LigandPNGBDBM26789(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataIC50: 540nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Bristol-Myers Squibb

LigandPNGBDBM26791(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-({4-[(2-...)
Affinity DataIC50: 1.60E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Bristol-Myers Squibb

LigandPNGBDBM26793(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataIC50: 4.60E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Bristol-Myers Squibb

LigandPNGBDBM26806((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...)
Affinity DataIC50: 8.00E+3nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Bristol-Myers Squibb

LigandPNGBDBM26789(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Bristol-Myers Squibb

LigandPNGBDBM26791(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-({4-[(2-...)
Affinity DataKi:  1.87E+3nM ΔG°:  -32.7kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Bristol-Myers Squibb

LigandPNGBDBM26789(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataKi:  1.96E+3nM ΔG°:  -32.6kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Bristol-Myers Squibb

LigandPNGBDBM26791(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-({4-[(2-...)
Affinity DataKi:  2.61E+3nM ΔG°:  -31.9kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Bristol-Myers Squibb

LigandPNGBDBM26793(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataKi: >3.06E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Bristol-Myers Squibb

LigandPNGBDBM26793(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataKi:  3.50E+3nM ΔG°:  -31.1kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Bristol-Myers Squibb

LigandPNGBDBM26793(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataKi:  3.92E+3nM ΔG°:  -30.9kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Bristol-Myers Squibb

LigandPNGBDBM26789(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataKi:  4.08E+3nM ΔG°:  -30.8kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Bristol-Myers Squibb

LigandPNGBDBM26789(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataKi: >4.50E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb

LigandPNGBDBM26789(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataKi: >5.03E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb

LigandPNGBDBM26791(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-({4-[(2-...)
Affinity DataKi: >5.03E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb

LigandPNGBDBM26793(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataKi: >5.03E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Bristol-Myers Squibb

LigandPNGBDBM26791(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-({4-[(2-...)
Affinity DataKi:  5.86E+3nM ΔG°:  -29.9kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed