Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50000698
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50007518(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
Affinity DataKi:  0.190nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50007522(CHEMBL289330 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylm...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008783(CHEMBL42448 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...)
Affinity DataKi:  0.25nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008782(CHEMBL44237 | EPIDEPRIDE | Epidepride;N-(1-Ethyl-p...)
Affinity DataKi:  0.270nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008782(CHEMBL44237 | EPIDEPRIDE | Epidepride;N-(1-Ethyl-p...)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50007522(CHEMBL289330 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylm...)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008786(CHEMBL43506 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008786(CHEMBL43506 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008783(CHEMBL42448 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50007518(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008785(CHEMBL42953 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-...)
Affinity DataKi:  1.20nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008788(CHEMBL42260 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008784(CHEMBL288704 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5...)
Affinity DataKi:  1.40nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM31046(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards Alpha-2 adrenergic receptor, using [3H]- atipamezole as radioligand from rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataKi:  1.80nMAssay Description:Compound was evaluated for binding affinity towards Dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the absence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataKi:  2.20nMAssay Description:Compound was evaluated for binding affinity towards Dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008785(CHEMBL42953 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50008782(CHEMBL44237 | EPIDEPRIDE | Epidepride;N-(1-Ethyl-p...)
Affinity DataKi:  5nMAssay Description:binding affinity towards alpha-2 adrenergic receptor, using [3H]- atipamezole as radioligand from rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008784(CHEMBL288704 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008787(CHEMBL43552 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2,...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50005118(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataKi:  8.30nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50008786(CHEMBL43506 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...)
Affinity DataKi:  9.5nMAssay Description:binding affinity towards alpha-2 adrenergic receptor, using [3H]- atipamezole as radioligand from rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50008783(CHEMBL42448 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...)
Affinity DataKi:  11nMAssay Description:binding affinity towards alpha-2 adrenergic receptor, using [3H]- atipamezole as radioligand from rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50005118(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50007523(CHEMBL295621 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50453046(CHEMBL2114461)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50453047(CHEMBL2114460)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed