Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 2468
LigandPNGBDBM20971(3,6-dimethyl-4-(pentan-3-yloxy)-N-(2,4,6-trimethyl...)
Affinity DataIC50: 3.70nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20966(2-Aryloxy-4-alkylaminopyridine, 3a | 3,6-dimethyl-...)
Affinity DataIC50: 5.10nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM20968(2-(4-bromo-2,6-dimethylphenoxy)-3,6-dimethyl-N-(pe...)
Affinity DataIC50: 5.60nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20969(methyl 2-(4-chloro-2,6-dimethylphenoxy)-4-{[(2S)-1...)
Affinity DataIC50: 6.40nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20933(JMC511377 Compound 2 | 3,6-dimethyl-4-(pentan-3-yl...)
Affinity DataIC50: 6.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20967(2-(4-chloro-2,6-dimethylphenoxy)-3,6-dimethyl-N-(p...)
Affinity DataIC50: 7.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20970(2-(4-chloro-2,6-dimethylphenoxy)-4-{[(2S)-1-hydrox...)
Affinity DataIC50: 31nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20972(3,6-dimethyl-4-N-(pentan-3-yl)-2-N-(2,4,6-trimethy...)
Affinity DataIC50: 750nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed