Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50038752
TargetEpidermal growth factor receptor(Human)
Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM4367((3Z)-2-amino-3-[(3,4,5-trihydroxyphenyl)methyliden...)
Affinity DataIC50: 800nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM4363(alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM24941(CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/Cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 3(Human)
Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ERK1/MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInsulin receptor(Human)
Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM4363(alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...)
Affinity DataIC50: 6.40E+5nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed