Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 3278
TargetBile acid receptor(Human)
Merck Research Laboratories

LigandPNGBDBM30326(MFA-1)
Affinity DataEC50:  16.9nMpH: 7.0 T: 2°CAssay Description:To each well of a 96-well assay plate, assay buffer was added containing purified GST-FXR, Eu-labeled anti-GST antibody (Perkin-Elmer), streptavidin-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Merck Research Laboratories

LigandPNGBDBM30327(MFA-2)
Affinity DataEC50:  509nMpH: 7.0 T: 2°CAssay Description:To each well of a 96-well assay plate, assay buffer was added containing purified GST-FXR, Eu-labeled anti-GST antibody (Perkin-Elmer), streptavidin-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Merck Research Laboratories

LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  8.30E+3nMpH: 7.0 T: 2°CAssay Description:To each well of a 96-well assay plate, assay buffer was added containing purified GST-FXR, Eu-labeled anti-GST antibody (Perkin-Elmer), streptavidin-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBile acid receptor(Human)
Merck Research Laboratories

LigandPNGBDBM30328(MFA-3)
Affinity DatapH: 7.0 T: 2°CAssay Description:To each well of a 96-well assay plate, assay buffer was added containing purified GST-FXR, Eu-labeled anti-GST antibody (Perkin-Elmer), streptavidin-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2009
Entry Details Article
PubMed