Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50025904
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261157(5-(2-Ethoxy-5-(N-acetic acid,N'-5-(2-ethoxy-5-sulf...)
Affinity DataIC50: 38nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261649(5-{2-Ethoxy-5-[(4-(4-nitrophenyl))piperazinylsulph...)
Affinity DataIC50: 50nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 53nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261602(5-{2-Ethoxy-5-[(4-(2-fluorophenyl)piperazinylsulph...)
Affinity DataIC50: 60nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261603(5-{2-Ethoxy-5-[(4-(4-fluorophenyl)piperazinylsulph...)
Affinity DataIC50: 70nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261652(5-{2-Ethoxy-5-[(4-(1-(cyclohexyl))piperazinylsulph...)
Affinity DataIC50: 70nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261647(5-{2-Ethoxy-5-[(4-(3-chlorophenyl))piperazinylsulp...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261648(5-{2-Ethoxy-5-[(4-(4-chlorophenyl))piperazinylsulp...)
Affinity DataIC50: 140nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261574(5-{2-Ethoxy-5-[(4-(1-(2-methoxyphenyl))piperazinyl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261154(5-(2-Ethoxy-5-(N-phenyl-ethylenediamine-sulfonyl)p...)
Affinity DataIC50: 200nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261158(5-(2-Ethoxy-5-(N-ethanol,N'-5-(2-ethoxy-5-sulfonyl...)
Affinity DataIC50: 310nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261651(5-{2-Ethoxy-5-[(4-(1-piperonyl)piperazinylsulphony...)
Affinity DataIC50: 320nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261650(5-{2-Ethoxy-5-[4-(1-naphthyl)piperazinylsulphonyl]...)
Affinity DataIC50: 370nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261156(5-(2-Ethoxy-5-(N-acetic acid ethylenediamine-sulfo...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261155(5-(2-Ethoxy-5-(N-naphthyl-ethylenediamine-sulfonyl...)
Affinity DataIC50: 510nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
State University of Campinas

Curated by ChEMBL
LigandPNGBDBM50261653(4-Nitrooxy-butyric acid 2-{4-[4-ethoxy-3-(1-methyl...)
Affinity DataIC50: 530nMAssay Description:Inhibition of PDE5 in human platelets after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed