Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50026023
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248926(3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248955(3-((1-(4-methylbenzyl)piperidin-4-yl)methyl)benzo[...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248905(3-((1-benzylpiperidin-4-yl)methyl)benzo[d]oxazol-2...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248929(3-[[1-(4-Fluorobenzyl)piperidin-4-yl]methyl]benzo[...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248928(3-[[1-(2-Fluorobenzyl)piperidin-4-yl]methyl]benzo[...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248956(3-((1-(2,4-dimethylbenzyl)piperidin-4-yl)methyl)be...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248930(3-((1-(2-methylbenzyl)piperidin-4-yl)methyl)benzo[...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248906(3-((1-(2-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248927(3-[[1-(2,4-Dichlorobenzyl)piperidin-4-yl]methyl]be...)
Affinity DataKi:  258nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248958(3-((1-(biphenyl-4-ylmethyl)piperidin-4-yl)methyl)b...)
Affinity DataKi:  394nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248959(3-((1-(naphthalen-1-ylmethyl)piperidin-4-yl)methyl...)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50248957(3-[[1-(2,4,6-Trimethylbenzyl)piperidin-4-yl]methyl...)
Affinity DataKi:  6.23E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed