Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50026044
TargetKappa-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260633((S)-2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]i...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260633((S)-2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]i...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50: 0.650nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(5-chloro-2-[(1-ethyl-1-methylpropyl)thio]-6-[4-(2-...)
Affinity DataIC50: 0.660nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260633((S)-2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]i...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(5-chloro-2-[(1-ethyl-1-methylpropyl)thio]-6-[4-(2-...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260633((S)-2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]i...)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239745(2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...)
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260633((S)-2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]i...)
Affinity DataIC50: 5.30nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260630(2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239745(2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...)
Affinity DataIC50: 9.70nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260632(2-((1S,4S)-5-(6-chloro-2-(pentan-3-ylthio)-3H-benz...)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260630(2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260633((S)-2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]i...)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]diprenorphin from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260632(2-((1S,4S)-5-(6-chloro-2-(pentan-3-ylthio)-3H-benz...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260631(2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...)
Affinity DataIC50: 59nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260633((S)-2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]i...)
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]diprenorphin from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260631(2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...)
Affinity DataIC50: 73nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50: 97nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50: 180nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50260633((S)-2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]i...)
Affinity DataIC50: 238nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50: 1.20E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]diprenorphin from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50: 4.40E+3nMAssay Description:Displacement of [3H]diprenorphin from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed