Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50038575
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKd:  0.0970nMAssay Description:Binding affinity to human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKd:  0.150nMAssay Description:Binding affinity to human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi:  2nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKd:  2.20nMAssay Description:Binding affinity to human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKd:  2.70nMAssay Description:Binding affinity to human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity to human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM28582([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM28582([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM28582([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM28582([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi:  73nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi:  82nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi:  189nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi:  231nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi:  288nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to 5HT1E receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to 5HT1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to alpha 1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to serotonin uptake transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to 5HT5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to muscarinic M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to muscarinic M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50271706(N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-i...)
Affinity DataKi: >500nMAssay Description:Binding affinity to dopamine uptake transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed