Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50039264
TargetCell division cycle 7-related protein kinase(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 10nMAssay Description:Inhibition of cdc7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 20nMAssay Description:Inhibition of cdk9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of cdk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 34nMAssay Description:Inhibition of cdk9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 40nMAssay Description:Inhibition of cdk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 220nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 240nMAssay Description:Inhibition of cdk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 250nMAssay Description:Inhibition of cdk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 460nMAssay Description:Inhibition of cdk5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Mk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 875nMAssay Description:Inhibition of Cdk7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 980nMAssay Description:Inhibition of plk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKAalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of P38betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSTE20-like serine/threonine-protein kinase(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of STLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TAO3(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TAO3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRKAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ZAP70More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase NIM1(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek6(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nek6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cdk7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AlkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed