Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50026118
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267369((8R,9S,13S,14S,17R)-5',5',13-Trimethyl-4',5',6,7,8...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267368((8R,9S,13S,14S,17R)-5',13-Dimethyl-4',5',6,7,8,9,1...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267385((2'S,8R,9S,13S,14S)-13-methyl-4',5',6,7,8,9,11,12,...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267380((2'R,8R,9S,13S,14S)-3-hydroxy-5',13-dimethyl-4',5'...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267382((R/S)-(2'R,8R,9S,13S,14S)-3-hydroxy-4',13-dimethyl...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267362((2'S,8R,9S,13S,14S)-3-hydroxy-13-methyl-4',5',6,7,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267381((2'R,8R,9S,13S,14S)-3-hydroxy-5',5',13-trimethyl-4...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267363((2'S,8R,9S,13S,14S)-3-hydroxy-13-methyl-6,7,8,9,11...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267366((2'R,8R,9S,13S,14S)-3-hydroxy-13-methyl-6,7,8,9,11...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267384((4bS,6aS,6bS,11aS,12aS,12bR)-2-Hydroxy-6a-methyl-4...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267365((R/S)-(2'R,8R,9S,13S,14S)-methyl 3-hydroxy-13-meth...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Chul Research Center and University Laval

Curated by ChEMBL
LigandPNGBDBM50267383((R/S)-(2'R,8R,9S,13S,14S)-5'-allyl-3-hydroxy-13-me...)
Affinity DataIC50: 107nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed