Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50026310
TargetMitogen-activated protein kinase 9(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM15754((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...)
Affinity DataKd:  5.00E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM15754((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of p38alpha in hTERT-immortalized human HCA2 cells assessed as decrease in phosphorylated HSP27 level by ELISA in presence of anisomycinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM15754((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of p38alpha-induced TNFalpha production in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM15754((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of p38alpha-mediated IL1-beta production in peripheral mononucleocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM15754((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of p38alpha-mediated TNFalpha production in peripheral mononucleocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed