Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50026316
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244050(N-Cycloheptyl-2-[4-(cyclopentylamino)piperidine-1-...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244126(N-cycloheptyl-7-methoxy-2-(4-(pyrrolidin-1-yl)pipe...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244083(N-cycloheptyl-2-(4-(cyclopentyl(methyl)amino)piper...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243945(N-cycloheptyl-6,7-dimethoxy-2-(4-(piperidin-1-yl)p...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244125(N-cycloheptyl-6-methoxy-2-(4-(pyrrolidin-1-yl)pipe...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243946(N-cycloheptyl-2-(4-(4-fluoropiperidin-1-yl)piperid...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243945(N-cycloheptyl-6,7-dimethoxy-2-(4-(piperidin-1-yl)p...)
Affinity DataIC50: 73nMAssay Description:Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244381(N-Cyclooctyl-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpip...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244127(N-cycloheptyl-2-(4-(pyrrolidin-1-yl)piperidin-1-yl...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243996(N-Cycloheptyl-2-(4-isopropylpiperazine-1-yl)-6,7-d...)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243897(N-Cycloheptyl-2-[4-(dimethylamino)piperidine-1-yl]...)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244340(N-Cyclohexyl-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpip...)
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244167(N-cycloheptyl-2-(1-cyclohexylpiperidin-4-yl)-6,7-d...)
Affinity DataIC50: 510nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244124(N-cycloheptyl-2-(4-cyclohexylpiperazin-1-yl)-6,7-d...)
Affinity DataIC50: 550nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243996(N-Cycloheptyl-2-(4-isopropylpiperazine-1-yl)-6,7-d...)
Affinity DataIC50: 660nMAssay Description:Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243897(N-Cycloheptyl-2-[4-(dimethylamino)piperidine-1-yl]...)
Affinity DataIC50: 730nMAssay Description:Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244381(N-Cyclooctyl-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpip...)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244340(N-Cyclohexyl-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpip...)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed