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Found
17
Enz. Inhib. hit(s) with all data for entry = 50026464
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50236362
(N-(4-chlorophenyl)-6-(6,7-dimethoxyquinolin-4-ylox...)
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Affinity Data
IC50: 0.5nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
PDB
3D Structure (crystal)
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Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252470
(N-(4-chloro-3-(trifluoromethyl)phenyl)-2-((6,7-dim...)
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Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252506
(2-((6,7-dimethoxyquinolin-4-yl)methyl)-N-(4-fluoro...)
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Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252469
(2-((6,7-dimethoxyquinolin-4-yl)methyl)-N-(3-(trifl...)
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Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252507
(N-(4-tert-butylphenyl)-2-((6,7-dimethoxyquinolin-4...)
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Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252657
(2-((6,7-dimethoxyquinolin-4-yl)methyl)-N-(4-fluoro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252602
(2-((6,7-dimethoxyquinolin-4-yl)methyl)-1-oxo-N-(3-...)
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Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252603
(N-(4-chloro-3-(trifluoromethyl)phenyl)-2-((6,7-dim...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252505
(2-(quinolin-4-ylmethyl)-N-(3-(trifluoromethyl)phen...)
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Copy InChI
Affinity Data
IC50: 4nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252467
(N-(4-tert-butylphenyl)-2-(quinolin-4-ylmethyl)-1,2...)
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Affinity Data
IC50: 8nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252658
(N-(4-tert-butylphenyl)-2-((6,7-dimethoxyquinolin-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252548
(N-(benzo[d]thiazol-2-yl)-2-((6,7-dimethoxyquinolin...)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252601
(1-oxo-2-(quinolin-4-ylmethyl)-N-(3-(trifluoromethy...)
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Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252550
(N-cyclopropyl-2-((6,7-dimethoxyquinolin-4-yl)methy...)
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Affinity Data
IC50: 92nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252468
(N-(4-chlorophenyl)-2-((6,7-dimethoxyquinolin-4-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 165nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252549
(2-((6,7-dimethoxyquinolin-4-yl)methyl)-N-(pyridin-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 225nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50252551
(2-((6,7-dimethoxyquinolin-4-yl)methyl)-N-(2-methox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/11/2010
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL