Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50026552
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262934([3-(2-Ethoxyethyl)-2-methyl-5-(4-methylsulphonyl)p...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262933([1-(4-Fluoro)phenyl-2-methyl-5-(4-methylsulphonyl)...)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262990([2-Methyl-5-(4-methylsulphonyl)phenyl-1-phenyl-3-(...)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262992([1-(4-Fluoro)phenyl-2-methyl-5-(4-methylsulphonyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166278(ethyl 2-(2-methyl-5-(4-(methylsulfonyl)phenyl)-1-p...)
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262989([3-(2-Ethoxyethyl)-1-(4-Fluoro)phenyl-2-methyl-5-(...)
Affinity DataIC50: 47nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262931([2-Methyl-5-(4-methylsulphonyl)phenyl-3-(2-methoxy...)
Affinity DataIC50: 48nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262932([2-Methyl-5-(4-methylsulphonyl)phenyl-3-(2-methoxy...)
Affinity DataIC50: 49nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166281([5-(4-Methanesulfonyl-phenyl)-2-methyl-1-(4-triflu...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262935([3-(2-Ethoxyethyl)-2-methyl-5-(4-methylsulphonyl)p...)
Affinity DataIC50: 85nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262991([2-Methyl-5-(4-methylsulphonyl)phenyl-3-(2-n-propy...)
Affinity DataIC50: 110nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166276(ethyl 2-(2-methyl-5-(4-(methylsulfonyl)phenyl)-1-p...)
Affinity DataIC50: 480nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataIC50: 660nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on thrombin-induced TXB2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262990([2-Methyl-5-(4-methylsulphonyl)phenyl-1-phenyl-3-(...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on thrombin-induced TXB2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of COX1 in LPS-induced human whole blood assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262990([2-Methyl-5-(4-methylsulphonyl)phenyl-1-phenyl-3-(...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of COX1 in LPS-induced human whole blood assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262932([2-Methyl-5-(4-methylsulphonyl)phenyl-3-(2-methoxy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262931([2-Methyl-5-(4-methylsulphonyl)phenyl-3-(2-methoxy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166281([5-(4-Methanesulfonyl-phenyl)-2-methyl-1-(4-triflu...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166276(ethyl 2-(2-methyl-5-(4-(methylsulfonyl)phenyl)-1-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262933([1-(4-Fluoro)phenyl-2-methyl-5-(4-methylsulphonyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262934([3-(2-Ethoxyethyl)-2-methyl-5-(4-methylsulphonyl)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262935([3-(2-Ethoxyethyl)-2-methyl-5-(4-methylsulphonyl)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262989([3-(2-Ethoxyethyl)-1-(4-Fluoro)phenyl-2-methyl-5-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262990([2-Methyl-5-(4-methylsulphonyl)phenyl-1-phenyl-3-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262991([2-Methyl-5-(4-methylsulphonyl)phenyl-3-(2-n-propy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262992([1-(4-Fluoro)phenyl-2-methyl-5-(4-methylsulphonyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166278(ethyl 2-(2-methyl-5-(4-(methylsulfonyl)phenyl)-1-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed