Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50026582
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(N-[5-(9H-Carbazol-4-yloxy)pentyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 1.54nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(N-[4-(9H-Carbazol-4-yloxy)butyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 1.65nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263213(N-[3-(9H-Carbazol-4-yloxy)propyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 2.15nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263262(N-[6-(9H-Carbazol-4-yloxy)hexyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 2.57nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM10514(N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propan...)
Affinity DataIC50: 21.5nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 45.8nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263262(N-[6-(9H-Carbazol-4-yloxy)hexyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 137nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(N-[5-(9H-Carbazol-4-yloxy)pentyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 189nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(N-[4-(9H-Carbazol-4-yloxy)butyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 211nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263213(N-[3-(9H-Carbazol-4-yloxy)propyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 296nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 424nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263213(N-[3-(9H-Carbazol-4-yloxy)propyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 740nMAssay Description:Inhibition of NMDA NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM10514(N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propan...)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50062599(CHEMBL807 | Namenda | 3,5-Dimethyl-adamantan-1-yla...)
Affinity DataIC50: 9.52E+3nMAssay Description:Inhibition of NMDA NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263262(N-[6-(9H-Carbazol-4-yloxy)hexyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of NMDA NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(N-[5-(9H-Carbazol-4-yloxy)pentyl]-N'-(6-chloro-1,2...)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of NMDA NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(N-[4-(9H-Carbazol-4-yloxy)butyl]-N'-(6-chloro-1,2,...)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of NMDA NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed