Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50038637
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50050093((4-Chloro-6-methoxy-2-methyl-pyrimidin-5-yl)-imida...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50021809((2,6-Dichloro-4-iodo-phenyl)-imidazolidin-2-yliden...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50412317(CHEMBL468161)
Affinity DataKi:  6.03nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 expressed in rat PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM30712(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM31046(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Affinity DataKi:  11.4nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM81984(NSC_3519 | CAS_29110-47-2 | Guanfacine)
Affinity DataKi:  19.0nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50240671(CHEMBL1079 | Zanaflex | (5-Chloro-benzo[1,2,5]thia...)
Affinity DataKi:  28nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM96725(Guanabenz | 2-[(E)-(2,6-dichlorophenyl)methylidene...)
Affinity DataKi:  34.7nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50262233(efaroxane)
Affinity DataKi:  52.4nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-2-imidazoline | 2-(2,6-dic...)
Affinity DataKi:  55nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50262235(rilmenidine)
Affinity DataKi:  59.2nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50027060(2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imi...)
Affinity DataKi:  99nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50001922(Naphazoline | Albalon | Opcon | CHEMBL1706 | Nafaz...)
Affinity DataKi:  122nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50262238(2-(4-Chloro-1,3-dihydro-isoindol-2-ylamino)-4,5-di...)
Affinity DataKi:  232nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNischarin(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50019848(CHEMBL10316 | Idazoxan | US8633208, Idazoxan | 4,5...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed